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PEMFC is the promising technology for automotive applications with a large deployment horizon by 2030. However, in view of extending their use to a broad range of customers, progress have to be done in terms of cost, performance and durability. The FURTHER-FC project aims at understanding performance limitations due to the coupling between electrochemical and transport issues in the Cathode Catalyst Layer (CCL) which is the main bottleneck for future PEMFC. The comprehensive and innovative approach is based on unique and intensive fundamental characterizations coupled with advanced modelling, from sub-micrometer to its full thickness. The analysis are performed on CCL customized with different and original materials, and will cover structural 3D analysis of the CCL, local operando diagnostics (temperature, liquid water) in the CCL, advanced characterization of ionomer films, innovative diagnostics on transport limitations, fundamental electrochemistry. Advanced one and two-phase models will be used as a support to the experiments and benefit from the experiments for more reliable inputs, physics and validation. The approach will also address the durability issues thanks to the better understanding of the correlation between CCL microstructure, local conditions and properties. FURTHER-FC will propose and validate the performance and durability new ionomer and electrode structures specifically designed to prevent the limitations observed on current MEA, contributing to reach the MAWP targets for horizon 2024-2030. FURTHER-FC will benefit from the active role of renowned partners gathering significant experience on MEA manufacturing and testing (Toyota Europe, CEA, DLR), state-of-the Art experimental techniques (CEA, DLR, PSI, CNRS-IEM, Univ. of Esslingen, Imperial College of London) and modelling tools (CEA, DLR, CNRS-INPT) supported by international entities (Chemours-US, University of Calgary).

The objectives of the interdisciplinary project IQubits are to (i) develop and demonstrate experimentally high-temperature (high-T) Si and SiGe electron/hole-spin qubits and qubit integrated circuits (ICs) in commercial 22nm Fully-Depleted Silicon-on-Insulator (FDSOI) CMOS foundry technology as the enabling fundamental building blocks of quantum computing technologies, (ii) verify the scalability of these qubits to 10nm dimensions through fabrication experiments and (iii) prove through atomistic simulations that, at 2nm dimensions, they are suitable for 300K operation. The proposed 22nm FDSOI qubit ICs consist of coupled quantum-dot electron and hole spin qubits, placed in the atomic-scale channel of multi-gate n- and p-MOSFETs, and of 60-240GHz spin control/readout circuits integrated on the same die in state-of-the-art FDSOI CMOS foundry technology. To assess the impact of future CMOS scaling, more aggressively scaled Si-channel SOI and nitride-channel qubit structures will also be designed and fabricated in two experimental processes with 10nm gate half pitch. The latter will be developed in this project. The plan is for the III-nitrides (III-N) qubits to be ultimately grown on a SOI wafer, to be compatible with CMOS. Because of their larger bandgap, III-N hold a better prospect than Si and SiGe for qubits with larger coupling energy and mode energy splitting, and 300K operation. As a radical breakthrough, the fabricated qubits will feature coupling energies on the order of 0.25-1 meV corresponding to control frequencies in the 60-240GHz range, suitable for operation at 3–12 degrees Kelvin, two orders of magnitude higher than today's qubits. The tuned mm-wave circuits allow for 10-20ps spin control pulses which help to filter out wideband thermal noise and largely enhance the ratio between the gating and the decoherence times. Thermal noise filtering and fast control of the spin may lead to even higher temperature operation for a given energy-level splitting.

ePIcenter will create an interoperable cloud-based ecosystem of user-friendly extensible Artificial Intelligence-based logistics software solutions and supporting methodologies that will enable all players in global trade and international authorities to co-operate with ports, logistics companies and shippers, and to react in an agile way to volatile political and market changes and to major climate shifts impacting traditional freight routes. This will address the ever-increasing expectations of 21st century consumers for cheaper and more readily available goods and bring in Innovations in transport, such as hyperloops, autonomous/robotic systems (e.g. “T-pods”) and new last-mile solutions as well as technological initiatives such as blockchain, increased digitalisation, single windows, EGNOS positional precision and the Copernicus Earth Observation Programme. ePIcenter thus addresses MG-2-9-2019 of H2020 Mobility for Growth “InCo Flagship on Integrated multimodal, low-emission freight transport systems and logistics”, particularly in what refers to new logistics concepts, new disruptive technologies, new trade routes (including arctic routes and new Silk routes) and multimodal transfer zones. ePIcenter will speed up the path to a Physical Internet and will benefit peripheral regions and landlocked developing countries. ePIcenter will reduce fuel usage (and corresponding emissions) by 10-25%, lead to greater utilisation of greener modes of transport reducing long distance movements by trucks by 20-25% and ensure a smoother profile of arrivals at ports which will reduce congestion and waiting/turnaround times.

Combustible gases are one of the few elements that can really challenge the containment integrity. An appropriate management of the associated risk is paramount to avoid the potential release of large amounts of radioactive material to the environment. Surprisingly, the Severe Accident Management Guidelines (SAMGs) have not been updated according to the knowledge gained in the last decade and the database extension resulting from recent and ongoing projects. The AMHYCO project intends to respond to practical questions, such as the right timing and mode for actuation of containment safety systems (i.e., FCVS, sprays, fan coolers) to reduce as much as feasible the threat posed to containment integrity. To do so, all the available tools to enhance the present status (i.e., LP, 3D and CFD codes, together with experimentation and the best use of engineering judgement) are to be applied. Three specific objectives are set: • To improve the Severe Accident Management Guidelines (SAMGs) for both in-vessel and ex-vessel phases with respect to combustible gases risk management, using both numerical and experimental results. • To investigate experimentally phenomena that are difficult to predict numerically: H2/CO/H2O distribution and combustion and PARs behavior under realistic accidental conditions, taking into account the safety systems interaction. • To improve the predictability of the numerical tools - Lumped Parameter (LP), 3D containment and Computational Fluid Dynamic (CFD) codes - used for explosion hazard evaluation inside the reactor containment to gain relevance in supporting SAMGs design and development. The scope of this project is outlined by the most common reactor technology in the EU: PWRs. The whole project is structured in 7 WPs (coordination included) in which an entire WP is to be devoted to the enhancement of SAMGs. Finally, AMHYCO has received the NUGENIA label and 9 organizations have shown their interest with support letters .

The ARCSAR project will establish international best practice and propose innovation platforms for the professional security and emergency response institutions in the Arctic and the North-Atlantic. The focus is on increased interaction in targeted networks between the professional institutions, academia and the innovators in the preparedness service and equipment industry. The ARCSAR project will monitor research and innovation projects and recommend the uptake and the industrialization of results, express common requirements as regards innovations that could fill in capability and other gaps and improve their performance in the future, and indicate priorities as regards common capabilities, or interfaces among capabilities, requiring more standardization. The project will look into the need for enhanced measures to respond to composite challenges including surveillance of and mobilization in case of threat situations, and emergency response capability related to search and rescue (SAR), environmental protection, fire fighting, and actions against terror or other forms of destructive action.

Driven by a general movement in Asia to invest in Classical studies, the project Vietnamica aims for a historical and linguistic study of ancient, invaluable Vietnamese inscriptions, while also helping to determine a ground-breaking method for the use of epigraphic resources. In partnership with Han-Nôm Institute and Vietnam National University, the project is motivated by the recent divulgence of 40,000 paper stampings that reproduce the inscriptions engraved on the surfaces of 25,000 steles erected between the 16th to 20th century in Vietnam. These inscriptions, written in a complex Chinese embedded with the local vernacular, are conserved at the Han-Nôm Institute in Hanoi. Offering an unexpected counterpoint to existing official sources, these inscriptions prompt the study of rural inhabitants, monks and notables across an era of five centuries through their very own language. The project will produce a series of studies on popular Buddhism and its connection to the ancestor cult, donations and the role of women in the economy of gifting, and monetization and land property. Based on these themes, the project will record and analyze the logographic processes that the Vietnamese once used to transcribe the language they spoke. Such research - close to the field and to its people - was once a dream for scholars, and is now possible due to the corpus of stampings available. Characteristic of local histories, information is dispersed in fragments all throughout the corpus and it is first necessary to categorize the existing inscriptions. Vietnamica will rely on tools available through digital and computational humanities to construct a database of the stampings, connect it to data mapping, and on a more technical level, proceed with a segmentation of the text to allow for the automatic identification of the demotic characters. The results from the project will converge on a Platform (Vietnamica.eu) that is meant to remain accessible to researchers indefinitely.

Despite the revolution in functional genome analysis a wide gap in understanding associations between the (epi)genome and complex phenotypes of interest currently remains and impedes efficient use of annotated genomes for precision breeding. The BovReg consortium will provide a comprehensive map of functionally active genomic features in cattle and how their (epi)genetic variation in beef and dairy breeds translates into phenotypes. This constitutes key knowledge for biology-driven genomic prediction needed by scientific and industry livestock communities. The BovReg brings together a critical mass of experts in ruminant research and beyond encompassing bioinformatics, molecular and quantitative genetics, animal breeding, reproductive physiology, ethics and social science. Our 20 partners from the EU, Canada and Australia form a global interdisciplinary team, which builds on previous and running national and EU-funded projects and many established industry cooperations. In BovReg we will generate functional genome data based on FAANG core assays from representative bovine tissues and newly established cell lines covering different ontological stages and phenotypes applying novel bioinformatic pipelines. We will establish detailed knowledge on traits related to robustness, health and biological efficiency in cattle. Data, knowledge and protocols will be deposited in European biological archives, aiming to set up and maintain a knowledge hub and establish gold standards. Long-term availability of data and targeted dissemination and communication activities are guaranteed by EMBL-EBI, FAANG and EAAP. Our biology-driven genomic prediction tools will integrate biological knowledge on regulatory genomic variation into genomic selection schemes for local and global cattle populations. This improved knowledge will be useful for re-focussing cattle production, fully taking into account societal awareness, environmental and animal-welfare aspects and bio-efficiency.

Measuring and quantifying how a patient feels or functions during treatment is an important endpoint in cancer clinical trials. It is generally accepted that the collection of PRO data in cancer clinical trials allows the inclusion of the patient’s voice in the risk-benefit assessment of therapies. However, no standards exist on how to analyse, interpret or report health-related quality of life (HRQOL) and other patient-reported outcomes (PROs). This initiative wants to pursue efforts in addressing the urgent need for standardization, by setting clear and validated standards that are tailored to and endorsed by all relevant stakeholders. With a strong international and multi-stakeholder Consortium, the initiative aims at finding consensus on suitable methods to analyse valid PRO objectives in cancer randomized clinical trials (RCTs) and ways to communicate these PRO findings in a standardized way that is understandable to all. To achieve this aim, SISAQOL-IMI will identify valid PRO research objectives and match these with appropriate statistical methods for PRO analysis in cancer RCTs. Translation to the estimands framework will be provided. Furthermore, the possibility of extending these recommendations to single-arm trial designs will be explored. Recommendations on clinically meaningful change for PRO instruments, as well as design considerations and ways for assessing quality of collected PRO data will be developed, and tools and templates for presentation and visualization of PRO findings freely made available. Strong emphasis is put on continuous collaboration with patient advocacy representatives throughout the project. Increased interpretability, adoption and full use of PRO outcomes for all stakeholders is expected by providing consensus-based and validated recommendations and communication tools for PRO data, ultimately resulting in better communication and shared decision making, improved outcomes, treatment satisfaction and care.

Biofuels are one of few options for decarbonizing transport in the short to medium term. However, they are often criticised for indirect land use change (ILUC), which is critical due to lack of high quality agricultural land and increasing world population. At the same time, significant contaminated land areas remain unused. CERESiS aims to provide a win-win sustainable solution to both issues by facilitating land decontamination through phytoremediation, growing energy crops to produce clean biofuels. In the longer term, this will increase the land available for agriculture, while producing non-ILUC biofuel. The project is based on three pillars. The phytoremediation pillar will identify a range of promising energy crops, focusing on key contaminants worldwide. They will be trialed in North, South, Eastern Europe and Brazil, with samples characterised and converted to biofuels. The technological pillar will optimize two clean biofuel conversion technologies, Supercritical Water Gasification & Fast Pyrolysis integrated with novel contaminant separation technologies, focusing on eliminating, stabilising or retrieving the contaminants in an easy to manage form. The Decision Support pillar will develop an open access, modular and expandable Decision Support System able to identify optimal solutions for each application. It will incorporate land, phytoremediation, technological, economic, environmental parameters providing critical information to stakeholders & policy makers on the suitability of combinations of phytoremediation strategies and conversion technologies for particular sites, contaminants, environmental restrictions etc. It will include Techno-economic analysis of pathways, LCA & LCC, supply chain optimization, and performance assessment against SDG goals. Partners from five EU countries, Ukraine, Brazil and Canada representing the entire value chain collaborate for the development and assessment of the integrated pathways.