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Risk and prognostic factors for breast cancer of different immunohistochemical subtypes (504711)
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102 research outcomes, page 1 of 11
  • publication . Article . Preprint . 2020
    Open Access English
    Authors:
    Caroline J. Bull; Joshua A. Bell; Neil Murphy; Eleanor Sanderson; George Davey Smith; Nicholas J. Timpson; Barbara L. Banbury; Demetrius Albanes; Sonja I. Berndt; Stéphane Bézieau; ...
    Publisher: Umeå universitet, Onkologi
    Project: NIH | CORE--CELL CULTURE FACILI... (5P01CA074184-05), NIH | Multiethnic Cohort Study ... (5R37CA054281-13), NIH | Molecular pathological ep... (2U01CA137088-05), UKRI | Mendelian randomization t... (MC_UU_00011/1), NIH | DIET, HORMONES AND RISK O... (3P01CA087969-03S1), NIH | Core-004 (1P01CA196569-01A1), NIH | Hormones and Colon Cancer... (5R01CA076366-07), NIH | Diet, Genetic Susceptibil... (5R01CA072520-09), NIH | Inflammation and Colorect... (5R01CA137178-05), NIH | Regional Oncology Researc... (3P30CA006973-53S2),...

    Abstract Background Higher adiposity increases the risk of colorectal cancer (CRC), but whether this relationship varies by anatomical sub-site or by sex is unclear. Further, the metabolic alterations mediating the effects of adiposity on CRC are not fully understood. ...

  • publication . Article . 2020
    Open Access English
    Authors:
    Amy Moore; Eleanor Kane; Zhaoming Wang; Zhaoming Wang; Orestis A. Panagiotou; Orestis A. Panagiotou; Lauren R. Teras; Alain Monnereau; Alain Monnereau; Alain Monnereau; ...
    Persistent Identifiers
    Project: NIH | Chemokine Induced Hematop... (2R01HL069669-05A1), NIH | BIOCHEMICAL MARKERS IN TH... (5U01CA049449-07), NIH | Vitamin D, Related Genes ... (2R01CA098661-06A2), NIH | Experimental Pathology (5P30CA016087-32), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01PC067010-000), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01PC067009-007), NIH | Resequencing and Function... (7R01CA154643-03), NIH | Molecular Pathogenesis of... (1K08CA134919-01A2), NIH | SURVEILLANCE, EPIDEMIOLOG... (N01PC065064-004), NIH | Protocol Review and Monit... (3P30CA042014-23S1),...

    Although the evidence is not consistent, epidemiologic studies have suggested that taller adult height may be associated with an increased risk of some non-Hodgkin lymphoma (NHL) subtypes. Height is largely determined by genetic factors, but how these genetic factors ma...

  • publication . Other literature type . 2020
    Open Access
    Authors:
    Bull, Caroline J.; Bell, Joshua A.; Murphy, Neil; Sanderson, Eleanor; Smith, George Davey; Timpson, Nicholas J.; Banbury, Barbara L.; Albanes, Demetrius; Berndt, Sonja I.; Bézieau, Stéphane; ...
    Publisher: figshare
    Project: WT , NIH | SOUTHWEST ONCOLOGY GROUP ... (2U10CA037429-04), NIH | Lifestyle, genetics and c... (5K07CA190673-06), NIH | Genome Wide Association C... (5U01HG004446-04), NIH | CLUE STUDIES--EVALUATING ... (5U01CA086308-05), NIH | AROMATIC AMINES AND COLON... (5R01CA060987-03), NIH | The Epidemiology of Immun... (5R01CA197350-03), WT | Institutional Strategic S... (204813), UKRI | Mendelian randomization t... (MC_UU_00011/1), NIH | DIET, HORMONES AND RISK O... (3P01CA087969-03S1),...

    Additional file 2: Figure S1. Scatter plot of SNP-BMI and SNP-CRC associations. Figure S2. Scatter plot of SNP-BMI and SNP-CRC associations (female specific). Figure S3. Scatter plot of SNP-BMI and SNP-CRC associations (male specific). Figure S4. Scatter plot of SNP-BMI...

  • publication . Article . 2019
    Open Access English
    Authors:
    Stephanie A. Bien; Yu Ru Su; David V. Conti; Tabitha A. Harrison; Conghui Qu; Xingyi Guo; Yingchang Lu; Demetrius Albanes; Paul L. Auer; Barbara L. Banbury; ...
    Project: NIH | The Colon Cancer Family R... (2U24CA097735-06), NIH | Multiethnic Cohort Study ... (5R37CA054281-13), NIH | Molecular pathological ep... (2U01CA137088-05), NIH | The Colon Cancer Family R... (3U24CA074799-10S1), NIH | Endothelial-Interstitial ... (1R01HL143247-01), NIH | Lifestyle, genetics and c... (5K07CA190673-06), NIH | SURVEILLANCE, EPIDEMIOLOG... (N01PC067001-001), NIH | Long Term Multidisciplina... (5UM1CA186107-05), NIH | Detection of Colorectal C... (5U01CA164930-04), NIH | Diet, Activity, and Lifes... (5R01CA048998-15),...

    Genome-wide association studies have reported 56 independently associated colorectal cancer (CRC) risk variants, most of which are non-coding and believed to exert their effects by modulating gene expression. The computational method PrediXcan uses cis-regulatory varian...

  • publication . Article . Preprint . 2019
    Open Access English
    Authors:
    Xia Jiang; Hilary K. Finucane; Fredrick R. Schumacher; Stephanie L. Schmit; Younghun Han; Kyriaki Michailidou; Corina Lesseur; Joe Dennis; Graham Casey; Jeroen R. Huyghe; ...
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN025403-000), NIH | Studies of Occupational C... (1Z01CP010119-06), NIH | The Colon Cancer Family R... (2U24CA097735-06), NIH | Multiethnic Cohort Study ... (5R37CA054281-13), NIH | Molecular pathological ep... (2U01CA137088-05), NIH | International Partnership... (1D43TW009112-01A1), NIH | The Colon Cancer Family R... (3U24CA074799-10S1), NIH | Endothelial-Interstitial ... (1R01HL143247-01), NIH | Administrative Core (5P50CA097190-10),...

    Quantifying the genetic correlation between cancers can provide important insights into the mechanisms driving cancer etiology. Using genome-wide association study summary statistics across six cancer types based on a total of 296,215 cases and 301,319 controls of Europ...

  • publication . Article . 2018
    Open Access English
    Authors:
    Sonja Neumeyer; Barbara L. Banbury; Volker Arndt; Sonja I. Berndt; Stéphane Bézieau; Stephanie A. Bien; Daniel D. Buchanan; Katja Butterbach; Bette J. Caan; Peter T. Campbell; ...
    Publisher: Nature Publishing Group UK
    Project: NIH | The Colon Cancer Family R... (2U24CA097735-06), NIH | Multiethnic Cohort Study ... (5R37CA054281-13), NIH | Molecular pathological ep... (2U01CA137088-05), NIH | Tissue and Pathology Reso... (1P50CA127003-01), NIH | The Colon Cancer Family R... (3U24CA074799-10S1), NIH | Lifestyle, genetics and c... (5K07CA190673-06), NIH | MOFFITT CANCER CENTER SUP... (3P30CA076292-08S4), NHMRC | Risk and prognostic facto... (504711), NIH | Genome Wide Association C... (5U01HG004446-04), NIH | AROMATIC AMINES AND COLON... (5R01CA060987-03),...

    BACKGROUND: Substantial evidence supports an association between use of menopausal hormone therapy and decreased colorectal cancer (CRC) risk, indicating a role of exogenous sex hormones in CRC development. However, findings on endogenous oestrogen exposure and CRC are ...

  • publication . Article . 2018
    Open Access English
    Authors:
    Suzanne C. Dixon-Suen; Christina M. Nagle; Aaron P. Thrift; Paul D.P. Pharoah; Ailith Ewing; Celeste Leigh Pearce; Wei Zheng; Georgia Chenevix-Trench; Peter A. Fasching; Matthias W. Beckmann; ...
    Persistent Identifiers
    Publisher: Nature Publishing Group
    Project: NIH | SURVEILLANCE, EPIDEMIOLOG... (N01PC067001-001), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN025403-000), NIH | Mayo Clinic SPORE in Ovar... (3P50CA136393-05S1), NHMRC | Towards cancer control: P... (199600), NIH | NORTHERN CALIFORNIA COOPE... (5U01CA069417-02), NIH | Discovery Expansion and R... (5U19CA148065-04), NIH | Steroid Hormone Genes and... (5R01CA112523-03), NIH | MHC-Restricted and MHC-No... (1P50CA159981-01A1), NIH | Core--Tissue Banking and ... (5P50CA105009-02),...

    Background:\ud \ud Observational studies suggest greater height is associated with increased ovarian cancer risk, but cannot exclude bias and/or confounding as explanations for this. Mendelian randomisation (MR) can provide evidence which may be less prone to bias.\ud M...

  • publication . Article . 2017
    Open Access English
    Authors:
    Sasha Bernatsky; Héctor A. Velásquez García; John J. Spinelli; Patrick M. Gaffney; Karin E. Smedby; Rosalind Ramsey-Goldman; Sophia S. Wang; Hans-Olov Adami; Demetrius Albanes; Emanuele Angelucci; ...
    Persistent Identifiers
    Project: NIH | EPIDEMIOLOGY OF NON-HODGK... (5R01CA045614-02), NIH | DIET, HORMONES AND RISK O... (3P01CA087969-03S1), NIH | Mayo Comprehensive Cancer... (3P30CA015083-37S2), NIH | The NYU Women's Health St... (5UM1CA182934-04), NIH | CALIFORNIAS PARTICIPATION... (5U58DP000807-03), NIH | SURVEILLANCE, EPIDEMIOLOG... (N01PC065064-004), NIH | Protocol Review and Monit... (3P30CA042014-23S1), NIH | Long Term Multidisciplina... (5UM1CA186107-05), NIH | Nutrional Epidemiology of... (1R25CA098566-01A1), NIH | Pooling and expansion of ... (5R01CA148690-03),...

    Objective: Determinants of the increased risk of diffuse large B-cell lymphoma (DLBCL) in SLE are unclear. Using data from a recent lymphoma genomewide association study (GWAS), we assessed whether certain lupus-related single nucleotide polymorphisms (SNPs) were also a...

  • publication . Article . 2017 . Embargo End Date: 23 Nov 2017
    Open Access English
    Authors:
    Olivier Brouckaert; Anja Rudolph; Annouschka Laenen; Renske Keeman; Manjeet K. Bolla; Qin Wang; Adelheid Soubry; Hans Wildiers; Irene L. Andrulis; Volker Arndt; ...
    Publisher: Apollo - University of Cambridge Repository
    Project: NWO | BBMRI-NL (2300154272), NHMRC | Towards cancer control: P... (199600), NHMRC | Australian Ovarian Cancer... (400413), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN025403-000), NIH | Risk and penetrance of mu... (5R01CA192393-02), NIH | Shanghai Breast Cancer St... (3R01CA064277-05S1), NIH | Consortium Study to Ident... (5R01CA148667-05), NIH | Cancer Risk Reduction and... (2R37CA070867-12), NIH | Identifying and validatin... (5R01CA176785-05), NIH | Cancer Center Support Gra... (3P30CA068485-21S4),...

    Background Previous studies have shown that reproductive factors are differentially associated with breast cancer (BC) risk by subtypes. The aim of this study was to investigate associations between reproductive factors and BC subtypes, and whether these vary by age at ...

  • publication . Article . 2017
    Open Access English
    Authors:
    Barrdahl, Myrto; Rudolph, Anja; Hopper, John L.; Southey, Melissa C.; Broeks, Annegien; Fasching, Peter A.; Beckmann, Matthias W.; Gago-Dominguez, Manuela; Castelao, J. Esteban; Guénel, Pascal; ...
    Publisher: John Wiley and Sons Inc.
    Project: NIH | Elucidating Loci Involved... (5U19CA148537-02), EC | BIORISE (669026), NIH | Ontario Familial Breast C... (5U01CA069467-16), NIH | Australian Breast Cancer ... (5U01CA069638-16), NIH | Discovery Expansion and R... (5U19CA148065-04), NIH | Risk and penetrance of mu... (5R01CA192393-02), NIH | Follow-up of Ovarian Canc... (3U19CA148112-04S1), NHMRC | Risk and prognostic facto... (504711), EC | COGS (223175), NIH | BRCA2 missense mutations ... (1R01CA116167-01A1),...

    This work was supported by NHS funding to the Royal Marsden/ICR NIHR Biomedical Research Centre a well as multiple funding agencies. For further information please visit the publisher's website.

102 research outcomes, page 1 of 11