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Nanopore array force spectroscopy chip for rapid clinical genotyping (5R01HG003248-05)
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3 research outcomes, page 1 of 1
  • publication . Other literature type . Article . 2011
    Open Access English
    Authors:
    Nahid N. Jetha; Christopher Feehan; Matthew Wiggin; Vincent Tabard-Cossa; Andre Marziali;
    Persistent Identifiers
    Project: NSERC , NIH | Nanopore array force spec... (5R01HG003248-05), NSERC , NIH | Nanopore array force spec... (5R01HG003248-05)

    AbstractA detailed understanding of the kinetics of DNA motion though nanometer-scale pores is important for the successful development of many of the proposed next-generation rapid DNA sequencing and analysis methods. Many of these approaches require DNA motion through...

  • publication . Article . Other literature type . 2008
    Open Access
    Authors:
    Matthew Wiggin; Carolina Tropini; Vincent Tabard-Cossa; Nahid N. Jetha; Andre Marziali;
    Persistent Identifiers
    Publisher: Elsevier BV
    Project: NSERC , NIH | Nanopore array force spec... (5R01HG003248-05)

    AbstractThroughput and resolution of DNA sequence detection technologies employing nanometer scale pores hinge on accurate kinetic descriptions of DNA motion in nanopores. We present the first detailed experimental study of DNA escape kinetics from α-hemolysin nanopores...

  • publication . Other literature type . Article . 2007
    Open Access English
    Authors:
    Carolina Tropini; Andre Marziali;
    Persistent Identifiers
    Publisher: The Biophysical Society. Published by Elsevier Inc.
    Project: NIH | Nanopore array force spec... (5R01HG003248-05)

    AbstractThe need for low-cost DNA sequence detection in clinical applications is driving development of new technologies. We demonstrate a method for detection of mutations in a DNA sequence purely by electronic means, and without need for fluorescent labeling. Our meth...

3 research outcomes, page 1 of 1