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61 research outcomes, page 1 of 7
  • publication . Preprint . 2018
    Open Access English
    Authors:
    Checcucci, Alice; diCenzo, George C.; Ghini, Veronica; Bazzicalupo, Marco; Becker, Anke; Decorosi, Francesca; Döhlemann, Johannes; Fagorzi, Camilla; Finan, Turlough M.; Fondi, Marco; ...
    Persistent Identifiers
    Publisher: Cold Spring Harbor Laboratory
    Project: NSERC

    AbstractMany bacteria, often associated with eukaryotic hosts and of relevance for biotechnological applications, harbour a multipartite genome composed by more than one replicon. Biotechnologically relevant phenotypes are often encoded by genes residing on the secondar...

  • publication . Article . 2019
    Open Access English
    Authors:
    Howard, S. Peter; Estrozi, Leandro F.; Bertrand, Quentin; Contreras-Martel, Carlos; Strozen, Timothy; Job, Viviana; Martins, Alexandre; Fenel, Daphna; Schoehn, Guy; Dessen, Andréa;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: NSERC , ANR | HemoPseudo (ANR-15-CE11-0018)

    The type II secretion system (T2SS) is a cell envelope-spanning macromolecular complex that is prevalent in Gram-negative bacterial species. It serves as the predominant virulence mechanism of many bacteria including those of the emerging human pathogens Vibrio vulnific...

  • publication . Article . Other literature type . 2015 . Embargo End Date: 16 Jan 2018
    Open Access
    Authors:
    Huaying Zhao; Rodolfo Ghirlando; Carlos Alfonso; Fumio Arisaka; Ilan Attali; David L. Bain; Marina Bakhtina; Donald F. Becker; Gregory J. Bedwell; Ahmet Bekdemir; ...
    Publisher: Apollo - University of Cambridge Repository
    Project: NIH | SPECIFICITY OF INTERCALAT... (5R01CA035635-13), NIH | Structure and Relations o... (5R01GM015792-39), NIH | Mechanisms for Histone H2... (5R01GM095822-08), NIH | Structure and Function of... (3R01GM067777-07S1), NIH | COBRE on Membrane Protein... (5P30GM103519-04), NIH | Bacterial Expression Core (5P50GM082545-02), NIH | REGULATION OF UBIQUITINAT... (5R01GM109102-04), NIH | The chaperone function of... (5F31GM105363-02), NIH | MOLECULAR INTERACTION IN ... (2R01GM029158-19)

    Peer reviewed

  • publication . Article . 2018
    Open Access
    Authors:
    Grimes, Jonathan M.; Hall, David R.; Ashton, Alun W.; Evans, Gwyndaf; Owen, Robin L.; Wagner, Armin; McAuley, Katherine E.; von Delft, Frank; Orville, Allen M.; Sorensen, Thomas; ...
    Persistent Identifiers
    Publisher: International Union of Crystallography (IUCr)

    Macromolecular crystallography (MX) has been a motor for biology for over half a century and this continues apace. A series of revolutions, including the production of recombinant proteins and cryo-crystallography, have meant that MX has repeatedly reinvented itself to ...

  • publication . Article . Other literature type . 2013
    Open Access English
    Authors:
    Enrico Ravera; Björn Corzilius; Vladimir K. Michaelis; Camilla Rosa; Robert G. Griffin; Claudio Luchinat; Ivano Bertini;
    Persistent Identifiers
    Project: EC | BIO-NMR (261863), EC | INSTRUCT (211252), NIH | Center for Magnetic Reson... (5P41EB002026-31), NSERC , EC | EAST-NMR (228461), NIH | Solid State NMR Studies o... (2R01EB001960-33A2), NIH | High Field DNP and EPR in... (2R01EB002804-27)

    Using the 480 kDa iron-storage protein complex, apoferritin (ApoF), as an example, we demonstrate that sizable dynamic nuclear polarization (DNP) enhancements can be obtained on sedimented protein samples. In sedimented solute DNP (SedDNP), the biradical polarizing agen...

  • publication . Article . 2016
    Open Access English
    Authors:
    Eaazhisai Kandiah; Diego Carriel; Julien Pérard; Hélène Malet; Maria Bacia; Kaiyin Liu; Sze W. S. Chan; Walid A. Houry; Sandrine Ollagnier de Choudens; Sylvie Elsen; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: EC | Chap4Resp (647784), ANR | acidstress (ANR-12-JSV8-0002), CIHR , ANR | ARCANE (ANR-11-LABX-0003), NSERC

    International audience; The inducible lysine decarboxylase LdcI is an important enterobacterial acid stress response enzyme whereas LdcC is its close paralogue thought to play mainly a metabolic role. A unique macromolecular cage formed by two decamers of the Escherichi...

  • publication . Article . 2020
    Open Access
    Authors:
    Stephen D. Carter; Cheri M. Hampton; Robert Langlois; Roberto Melero; Zachary J. Farino; Michael J. Calderon; Wen Li; Callen T. Wallace; Ngoc-Han Tran; Robert A. Grassucci; ...
    Persistent Identifiers
    Publisher: American Association for the Advancement of Science (AAAS)
    Project: NIH | Dual-Beam Scanning Electr... (1S10RR029300-01), NIH | National Resource for Aut... (7P41GM103310-14), NIH | JEOL JEM-1011 Transmissio... (1S10RR019003-01), NIH | Bacterial Expression Core (5P50GM082545-02), NIH | The Role of NgR Mediated ... (1R56AG058593-01), EC | QSOX1BIOFUNC (310649), NIH | Request for Ultracryomicr... (1S10RR025488-01), NIH | MICROPLATE SCINTILLATION/... (1S10RR013039-01), NSF | Investigation of the Regu... (1408986), NIH | Revealing Novel Mechanism... (5K08DA031241-02),...

    The endoplasmic reticulum (ER) is a highly dynamic network of membranes. Here, we combine live-cell microscopy with in situ cryo-electron tomography to directly visualize ER dynamics in several secretory cell types including pancreatic β-cells and neurons under near-nat...

  • publication . Doctoral thesis . 2017
    English
    Authors:
    Tsouroula, Aikaterini;
    Publisher: HAL CCSD
    Project: CIHR , EC | DDR IN LYMPHOCYTES (627187), NIH | Mechanistic derivation of... (1DP2HD087943-01), NSERC

    Heterochromatin is the tightly packed form of repetitive DNA, essential for cell viability. Its highly compacted and repetitive nature renders DSB repair a challenging process that cells need to overcome in order to maintain their genome integrity. Developing a highly s...

  • publication . Article . 2019
    Open Access English
    Authors:
    Vaněk, Ondřej; Celadova, Petra; Skořepa, Ondřej; Bláha, Jan; Kalousková, Barbora; Dvorská, Anna; Poláchová, Edita; Pucholtová, Helena; Kavan, Daniel; Pompach, Petr; ...
    Persistent Identifiers
    Publisher: Nature Publishing Group UK

    Abstract Working at the border between innate and adaptive immunity, natural killer (NK) cells play a key role in the immune system by protecting healthy cells and by eliminating malignantly transformed, stressed or virally infected cells. NK cell recognition of a targe...

  • other research product . 2006
    Open Access English
    Authors:
    Koufogiannakis, Denise; Wiebe, Natasha;

    Objective ‐ The objective of this systematic review was to assess which library instruction methods are most effective for improving the information skills of students at an introductory, undergraduate level, using cognitive outcomes (measuring changes in knowledge). Th...

61 research outcomes, page 1 of 7