Abstract Aims To describe heparin dosing requirements in patients who underwent catheter ablation of atrial fibrillation with uninterrupted anticoagulation using dabigatran etexilate (dabigatran) or warfarin to attain therapeutic activated clotting time (ACT) in the RE...

Abstract Background Sub-Saharan Africa is home to approximately 55 million orphaned children. The growing orphan crisis has overwhelmed many communities and has weakened the ability of extended families to meet traditional care-taking expectations. Other models of care...

The Ediacaran period began with the deglaciation of the ca. 635 Ma Marinoan snowball Earth and the deposition of cap dolostones on continental shelves worldwide during post-glacial sea-level rise. These carbonates sharply overlie glacial sediments deposited at low pale-...

In December 2005, 11 Canadian hematologists met to develop an evidence-based clinical practice guideline that would address the diagnosis, monitoring, management, and rationale for the treatment of transfusional iron overload in patients with myelodysplastic syndromes (...

An individual-based model was developed to simulate growth of the hard clam, Mercenaria mercenaria, in response to temperature, salinity and food supply conditions. Unique characteristics of the model are that: (1) length and tissue weight are related only by condition ...

1 Shanley, F., Weight Strength Analysis of Aircraft Structures, 1st ed., McGraw-Hill, New York, 1952; 2nd ed., Dover, New York, 1960. 2 Vinson, J. R. and Shore, S., "Bibliography on Methods of Structural Optimization for Flat Sandwich Panels," NAECASL-1082, April 1965, ...

53BP1 (also called TP53BP1) is a chromatin-associated factor that promotes immunoglobulin class switching and DNA double-strand-break (DSB) repair by non-homologous end joining. To accomplish its function in DNA repair, 53BP1 accumulates at DSB sites downstream of the R...