To identify genetic variants associated with birth weight, we meta-analyzed six genome-wide association (GWA) studies (n = 10,623 Europeans from pregnancy/birth cohorts) and followed up two lead signals in 13 replication studies (n = 27,591). rs900400 near LEKR1 and CCN...

Pathology of BRCA1 and BRCA2 MBCs and ORs in predicting BRCA2 mutation carrier status. (DOCX 20 kb)

Interactions of monomeric alpha-synuclein (alphaS) with lipid membranes have been suggested to play an important role in initiating aggregation of alphaS. We have systematically analyzed the distribution and self-assembly of monomeric alphaS on supported lipid bilayers....

A series of 4,4′-disubstituted organic−organometallic stilbenes, i.e., the 4′-substituted stilbenoid-NCN-pincer platinum(II) complexes [PtCl(NCN-R-4)] (NCN-R-4 = [C6H2(CH2NMe2)2-2,6-R-4]− in which R = C2H2C6H4-R′-4′ with R′ = NPh2, NMe2, OMe, SiMe3 H, I, CN, NO2) (1−8),...

Walking ability is frequently assessed with the 10-meter walking test (10MWT), which may be instrumented with multiple Kinect v2 sensors to complement the typical stopwatch-based time to walk 10 meters with quantitative gait information derived from Kinect’s 3D body poi...

The authors have argued elsewhere that the attentional blink (AB; i.e., reduced target detection shortly after presentation of an earlier target) arises from blocked or disrupted perceptual input in response to distractors presented between the targets. When targets rep...

Numerous genetic and environmental factors contribute to psychiatric disorders and other brain disorders. Common risk factors likely converge on biological pathways regulating the optimization of brain structure and function across the lifespan. Here, using structural m...

ABSTRACT DNA replication during S phase involves thousands of replication forks that must be coordinated to ensure that every DNA section is replicated only once. The minichromosome maintenance proteins, MCM2 to MCM7, form a heteromeric DNA helicase required for both th...

The Herschel Orion Protostar Survey obtained well-sampled 1.2 - 870 micron spectral energy distributions (SEDs) of over 300 protostars in the Orion molecular clouds, home to most of the young stellar objects (YSOs) in the nearest 500 pc. We plot the bolometric luminosit...