Abstract Patients with peripheral artery disease who undergo urgent or emergent lower extremity revascularization have the highest risk of major adverse cardiac and limb events. Although available evidence suggests that antithrombotic therapy reduces this risk, optimal ...

Background Reports addressing treatment of in-stent restenosis (ISR) are principally derived from clinical trials. Objectives To characterize the spectrum of ISR in an unselected population, and to explore clinical and angiographic factors determining management. Method...

ABSTRACT Background: Although insufficient maternal cardiac output (CO) has been implicated in poor outcomes in mothers with heart disease (HD), maternal-fetal interactions remain incompletely understood. We sought to quantify maternal-fetal hemodynamics using magnetic ...

Background In randomized trials, paclitaxel-eluting stents (PES) have been shown to be superior to bare metal stents (BMS) in reducing restenosis. However, the effectiveness of PES in patients treated during routine practice has not been fully established. Methods A ret...

Abstract Background Using standard cutoffs derived from healthy adults, high-sensitivity cardiac troponin T (hs-cTnT) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are frequently elevated in patients with reduced glomerular filtration rate (GFR), with unclea...

Abstract Antiplatelet agents are a cornerstone of therapy for patients with atherosclerotic vascular disease. There is presently a lack of comprehensive guidelines focusing on the use of antiplatelet drugs in patients currently manifesting or at elevated risk of cardiov...

This review addresses the rationale for lowering dietary sodium intake in Canada and recent progress in this direction. Data from trials involving moderate and sustained (≥ 4 weeks) reductions in sodium intake demonstrated significant dose-dependent effects on blood pre...

Transventricular Crushing and Extrication of Embolized Transcatheter Aortic Valve Prosthesis Christopher Tarola, MD, Bob Kiaii, MD, FRCSC, Patrick Teefy, MD, FRCPC, Pantelis Diamantorous, MD, FRCPC, Daniel Bainbridge, MD, FRCPC, Philip M. Jones, MD, FRCPC, Ivan Iglesias...