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Canada
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2018-2022
National Institutes of Health
Alzheimers Disease Neuroimaging Initiative
English

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Empirical examination of the replicability of associations between brain structure and psychological variables
appsOther research productkeyboard_double_arrow_right Other ORP type 2019 Belgium English NIH | Alzheimers Disease Neuroi..., EC | HBP SGA1, EC | HBP SGA2 +1 projects
NIH| Alzheimers Disease Neuroimaging Initiative ,
EC| HBP SGA1 ,
EC| HBP SGA2 ,
CIHR
Authors: Kharabian Masouleh, Shahrzad; Eickhoff, Simon; Hoffstaedter, Felix; Genon, Sarah;
Kharabian Masouleh, Shahrzad; Eickhoff, Simon; Hoffstaedter, Felix; Genon, Sarah;
handle: 2268/234053
handle: 2268/234053
Linking interindividual differences in psychological phenotype to variations in brain structure is an old dream for psychology and a crucial question for cognitive neurosciences. Yet, replicability of the previously-reported “structural brain behavior” (SBB)-associations has been questioned, recently. Here, we conducted an empirical investigation, assessing replicability of SBB among heathy adults. For a wide range of psychological measures, the replicability of associations with gray matter volume was assessed. Our results revealed that among healthy individuals 1) finding an association between performance at standard psychological tests and brain morphology is relatively unlikely 2) significant associations, found using an exploratory approach, have overestimated effect sizes and 3) can hardly be replicated in an independent sample. After considering factors such as sample size and comparing our findings with more replicable SBB-associations in a clinical cohort and replicable associations between brain structure and non-psychological phenotype, we discuss the potential causes and consequences of these findings.
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The following results are related to Canada. Are you interested to view more results? Visit OpenAIRE - Explore.

1 Research products

Empirical examination of the replicability of associations between brain structure and psychological variables
appsOther research productkeyboard_double_arrow_right Other ORP type 2019 Belgium English NIH | Alzheimers Disease Neuroi..., EC | HBP SGA1, EC | HBP SGA2 +1 projects
NIH| Alzheimers Disease Neuroimaging Initiative ,
EC| HBP SGA1 ,
EC| HBP SGA2 ,
CIHR
Authors: Kharabian Masouleh, Shahrzad; Eickhoff, Simon; Hoffstaedter, Felix; Genon, Sarah;
Kharabian Masouleh, Shahrzad; Eickhoff, Simon; Hoffstaedter, Felix; Genon, Sarah;
handle: 2268/234053
handle: 2268/234053
Linking interindividual differences in psychological phenotype to variations in brain structure is an old dream for psychology and a crucial question for cognitive neurosciences. Yet, replicability of the previously-reported “structural brain behavior” (SBB)-associations has been questioned, recently. Here, we conducted an empirical investigation, assessing replicability of SBB among heathy adults. For a wide range of psychological measures, the replicability of associations with gray matter volume was assessed. Our results revealed that among healthy individuals 1) finding an association between performance at standard psychological tests and brain morphology is relatively unlikely 2) significant associations, found using an exploratory approach, have overestimated effect sizes and 3) can hardly be replicated in an independent sample. After considering factors such as sample size and comparing our findings with more replicable SBB-associations in a clinical cohort and replicable associations between brain structure and non-psychological phenotype, we discuss the potential causes and consequences of these findings.
Open Repository and ...arrow_drop_down
Open Repository and Bibliography - University of Liège
Other ORP type . 2019
Data sources: Open Repository and Bibliography - University of Liège
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citeCite
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Powered by BIP!
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Open Repository and ...arrow_drop_down
Open Repository and Bibliography - University of Liège
Other ORP type . 2019
Data sources: Open Repository and Bibliography - University of Liège
linkLink to
shareshareShare
citeCite
addClaim
Please grant OpenAIRE to access and update your ORCID works.
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Canada
Other research products
2018-2022
National Institutes of Health
Alzheimers Disease Neuroimaging Initiative
English

Empirical examination of the replicability of associations between brain structure and psychological variables

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Empirical examination of the replicability of associations between brain structure and psychological variables

Canada
Other research products
2018-2022
National Institutes of Health
Alzheimers Disease Neuroimaging Initiative
English