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description Publicationkeyboard_double_arrow_right Preprint , Article , Other literature type 2018 FranceCopernicus GmbH SNSF | Volcanic Eruptions and th..., SNSF | Future and Past Solar Inf..., EC | STRATOCLIM +1 projectsSNSF| Volcanic Eruptions and their impact on future Climate (VEC) ,SNSF| Future and Past Solar Influence on the Terrestrial Climate II ,EC| STRATOCLIM ,SNSF| Study to determine Spectral Solar Irradiance and its impact on the middle atmosphere (SIMA)Kévin Lamy; Thierry Portafaix; Béatrice Josse; Colette Brogniez; Sophie Godin-Beekmann; Hassan Bencherif; Laura E. Revell; Hideharu Akiyoshi; Slimane Bekki; Michaela I. Hegglin; Patrick Jöckel; Oliver Kirner; Virginie Marécal; Olaf Morgenstern; Andrea Stenke; Guang Zeng; N. Luke Abraham; Alexander T. Archibald; N. Butchart; Martyn P. Chipperfield; Glauco Di Genova; Makoto Deushi; Sandip Dhomse; Rong-Ming Hu; Douglas E. Kinnison; Martine Michou; Fiona M. O'Connor; Luke D. Oman; Giovanni Pitari; David A. Plummer; John A. Pyle; Eugene Rozanov; David Saint-Martin; Kengo Sudo; Taichu Tanaka; Daniele Visioni; Kohei Yoshida;We have derived values of the Ultraviolet Index (UVI) at solar noon using the Tropospheric Ultraviolet Model (TUV) driven by ozone, temperature and aerosol fields from climate simulations of the first phase of the Chemistry-Climate Model Initiative (CCMI-1). Since clouds remain one of the largest uncertainties in climate projections, we simulated only the clear-sky UVI. We compared the modelled UVI climatologies against present-day climatological values of UVI derived from both satellite data (the OMI-Aura OMUVBd product) and ground-based measurements (from the NDACC network). Depending on the region, relative differences between the UVI obtained from CCMI/TUV calculations and the ground-based measurements ranged between −5.9% and 10.6%. We then calculated the UVI evolution throughout the 21st century for the four Representative Concentration Pathways (RCPs 2.6, 4.5, 6.0 and 8.5). Compared to 1960s values, we found an average increase in the UVI in 2100 (of 2–4%) in the tropical belt (30°N-30°S). For the mid-latitudes, we observed a 1.8 to 3.4 % increase in the Southern Hemisphere for RCP 2.6, 4.5 and 6.0, and found a 2.3% decrease in RCP 8.5. Higher increases in UVI are projected in the Northern Hemisphere except for RCP 8.5. At high latitudes, ozone recovery is well identified and induces a complete return of mean UVI levels to 1960 values for RCP 8.5 in the Southern Hemisphere. In the Northern Hemisphere, UVI levels in 2100 are higher by 0.5 to 5.5% for RCP 2.6, 4.5 and 6.0 and they are lower by 7.9% for RCP 8.5. We analysed the impacts of greenhouse gases (GHGs) and ozone-depleting substances (ODSs) on UVI from 1960 by comparing CCMI sensitivity simulations (1960–2100) with fixed GHGs or ODSs at their respective 1960 levels. As expected with ODS fixed at their 1960 levels, there is no large decrease in ozone levels and consequently no sudden increase in UVI levels. With fixed GHG, we observed a delayed return of ozone to 1960 values, with a corresponding pattern of change observed on UVI, and looking at the UVI difference between 2090s values and 1960s values, we found an 8 % increase in the tropical belt during the summer of each hemisphere. Finally we show that, while in the Southern Hemisphere the UVI is mainly driven by total ozone column, in the Northern Hemisphere both total ozone column and aerosol optical depth drive UVI levels, with aerosol optical depth having twice as much influence on the UVI as total ozone column does.
https://doi.org/10.5... arrow_drop_down HAL Descartes; HAL-Pasteur; HAL-InsermArticle . 2018add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/acp-2018-525&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu10 citations 10 popularity Top 10% influence Average impulse Top 10% Powered by BIP!
more_vert https://doi.org/10.5... arrow_drop_down HAL Descartes; HAL-Pasteur; HAL-InsermArticle . 2018add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/acp-2018-525&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Other literature type , Preprint , Article 2022 Netherlands, Denmark, Netherlands, Netherlands, GermanyCopernicus GmbH ANR | RESTORE, EC | NunataryukANR| RESTORE ,EC| NunataryukMartine Lizotte; Bennet Juhls; Atsushi Matsuoka; Philippe Massicotte; Gaëlle Mével; David Obie James Anikina; Sofia Antonova; Guislain Bécu; Marine Béguin; Simon Bélanger; Thomas Bossé-Demers; Lisa Bröder; Flavienne Bruyant; Gwénaëlle Chaillou; Jérôme Comte; Raoul-Marie Couture; Emmanuel Devred; Gabrièle Deslongchamps; Thibaud Dezutter; Miles Dillon; David Doxaran; Aude Flamand; Frank Fell; Joannie Ferland; Marie-Hélène Forget; Michael Fritz; Thomas J. Gordon; Caroline Guilmette; Andrea Hilborn; Rachel Hussherr; Charlotte Irish; Fabien Joux; Lauren Kipp; Audrey Laberge-Carignan; Hugues Lantuit; Edouard Leymarie; Antonio Mannino; Juliette Maury; Paul Overduin; Laurent Oziel; Colin Stedmon; Crystal Thomas; Lucas Tisserand; Jean-Éric Tremblay; Jorien Vonk; Dustin Whalen; Marcel Babin;Climate warming and related drivers of soil thermal change in the Arctic are expected to modify the distribution and dynamics of carbon contained in perennially frozen grounds. Thawing of permafrost in the Mackenzie Delta region of northwestern Canada, coupled with increases in river discharge and coastal erosion, trigger the release of terrestrial organic matter (OMt) from the largest Arctic drainage basin in North America into the Arctic Ocean. While this process is ongoing, well-established, and its rate is accelerating, the fate of the newly-mobilized organic matter, as it transits from the watershed through the delta and into the marine system, remains poorly understood. In the framework of the European Horizon 2020 Nunataryuk programme, and as part of the Work Package 4 (WP4) Coastal Waters theme, four field expeditions were conducted in the Mackenzie Delta region and southern Beaufort Sea from April to September 2019. The temporal sampling design allowed the survey of ambient conditions in the coastal waters under full ice cover prior to the spring freshet, during ice break-up in summer, as well as anterior to the freeze-up period in fall. To capture the fluvial-marine transition zone, and with distinct challenges related to shallow waters and changing seasonal and meteorological conditions, the field sampling was conducted in close partnership with members of the communities of Aklavik, Inuvik and Tuktoyaktuk, using several platforms: helicopters, snowmobiles and small boats. Water column profiles of physical and optical variables were measured in situ, while surface water, groundwater and sediment samples were collected and preserved for the determination of the composition and sources of OMt, including particulate and dissolved organic carbon (POC, DOC), and chromophoric dissolved organic matter (CDOM), as well as a suite of physical, chemical and biological variables. Here we present an overview of the standardized datasets, including hydrographic profiles, remote sensing reflectance, temperature and salinity, particle absorption, nutrients, dissolved organic carbon, particulate organic carbon, particulate organic nitrogen, colored dissolved organic matter absorption, fluorescent dissolved organic matter intensity, suspended particulate matter, total particulate carbon, total particulate nitrogen, stable water isotopes, radon in water, bacterial abundance, and a string of phytoplankton pigments including total chlorophyll. Datasets and related metadata can be found in Juhls et al. 2021. https://doi.pangaea.de/10.1594/PANGAEA.937587.
Earth System Science... arrow_drop_down Electronic Publication Information CenterArticle . 2023Data sources: Electronic Publication Information CenterOnline Research Database In TechnologyArticle . 2023Data sources: Online Research Database In Technologyadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/essd-2022-163&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu2 citations 2 popularity Average influence Average impulse Average Powered by BIP!
more_vert Earth System Science... arrow_drop_down Electronic Publication Information CenterArticle . 2023Data sources: Electronic Publication Information CenterOnline Research Database In TechnologyArticle . 2023Data sources: Online Research Database In Technologyadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/essd-2022-163&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2018Medical Journals Sweden AB Authors: Alice Kieny; Valérie Kremer; Sophie Scheidecker; Dan Lipsker;Alice Kieny; Valérie Kremer; Sophie Scheidecker; Dan Lipsker;pmid: 29057423
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.2340/00015555-2822&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu2 citations 2 popularity Average influence Average impulse Average Powered by BIP!
more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.2340/00015555-2822&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2021 Canada, FranceConsortium Erudit Authors: Fabien Bourlon;Fabien Bourlon;doi: 10.7202/1074898ar
Avec la crise du coronavirus, les destinations lointaines de nature comme la Patagonie chilienne sont inquiètes d’un effondrement du tourisme. Les communautés locales, apeurées par les risques liés à l’accueil de visiteurs, se replient et se protègent. Les entrepreneurs espèrent un rapide retour à la « normalité » d’une zone relativement épargnée par la COVID-19, mais craignent la fin du boom touristique, car prendre l’avion restera anxiogène dans un contexte de pandémie. Ces destinations devraient recentrer leur offre afin de capter une clientèle de proximité, mais cela semble un défi peu rentable pour les zones isolées. Alors que les entrepreneurs affinent leur plan marketing et les services d’État leurs protocoles d’accueil sécurisés, les animateurs de projets touristiques écologiques, axés sur la conservation, le tourisme rural et les migrations d’agrément, font valoir leurs atouts. L’actuelle crise pourrait mettre fin au tourisme de masse, à l’hypermobilité vers des hauts lieux et aux projets basés sur la rentabilité. La crise socioenvironnementale globale est l’occasion de repenser les rapports à la nature et de renforcer les systèmes touristiques locaux, pensés comme des lieux de vie, basés sur des économies rurales respectueuses de l’environnement, les échanges culturels, scientifiques et traditionnels, attirants autant pour les clientèles nationales qu’étrangères. With the coronavirus crisis, remote nature destinations like Chilean Patagonia are worried of a possible collapse of tourism. Local communities, frightened by the risks of welcoming visitors, are withdrawing and protecting themselves. Entrepreneurs hope for a rapid return to “normality” in an area relatively untouched by COVID-19 but they fear the end of the tourism boom, as flying will remain an anxiety-provoking issue in a post-pandemic situation. These destinations have to refocus their offer in order to capture a national clientele, but this seems an unprofitable challenge for isolated areas. While entrepreneurs are refining their marketing plans and government services are establishing their secure reception protocols, leaders of ecological and conservation tourism projects along with rural tourism and leisure migration stakeholders are highlighting their assets. The current crisis could put an end to mass tourism, hypermobilities, projects based on high profitability and overtourism in iconic places. In that sense, the present global socioenvironmental crisis is an opportunity to rethink our relationship with nature and seek ways to strengthen local tourism systems, conceived as places to live and based on environmentally friendly rural economies, cultural, scientific, and traditional exchanges, attractive both to national and foreign visitors.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.7202/1074898ar&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu3 citations 3 popularity Top 10% influence Average impulse Average Powered by BIP!
more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.7202/1074898ar&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Preprint 2015 FranceEDP Sciences NSERC, ANR | TUMSENSERC ,ANR| TUMSEFabrice Martins; A. Hervé; J. C. Bouret; W. L. F. Marcolino; Gregg A. Wade; Coralie Neiner; Evelyne Alecian; Jason Grunhut; Véronique Petit;The evolution of massive stars is still partly unconstrained. Mass, metallicity, mass loss and rotation are the main drivers of stellar evolution. Binarity and magnetic field may also significantly affect the fate of massive stars. Our goal is to investigate the evolution of single O stars in the Galaxy. For that, we use a sample of 74 objects comprising all luminosity classes and spectral types from O4 to O9.7. We rely on optical spectroscopy obtained in the context of the MiMeS survey of massive stars. We perform spectral modelling with the code CMFGEN. We determine the surface properties of the sample stars, with special emphasis on abundances of carbon, nitrogen and oxygen. Most of our sample stars have initial masses in the range 20 to 50 Msun. We show that nitrogen is more enriched and carbon/oxygen more depleted in supergiants than in dwarfs, with giants showing intermediate degrees of mixing. CNO abundances are observed in the range of values predicted by nucleosynthesis through the CNO cycle. More massive stars, within a given luminosity class, appear to be more chemically enriched than lower mass stars. We compare our results with predictions of three types of evolutionary models and show that, for two sets of models, 80% of our sample can be explained by stellar evolution including rotation. The effect of magnetism on surface abundances is unconstrained. Our study indicates that, in the 20-50 Msun mass range, the surface chemical abundances of most single O stars in the Galaxy are fairly well accounted for by stellar evolution of rotating stars. Comment: 15 pages, 12 figures. Accepted in Astronomy & Astrophysics
Astronomy and Astrop... arrow_drop_down add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1051/0004-6361/201425173&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu89 citations 89 popularity Top 10% influence Top 10% impulse Top 1% Powered by BIP!
more_vert Astronomy and Astrop... arrow_drop_down add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1051/0004-6361/201425173&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2019Springer Science and Business Media LLC Pierre-Emmanuel Bouet; Hugo Madar; Alizée Froeliger; Hady El Hachem; Elsa Schinkel; Aurelien Mattuizi; Loïc Sentilhes;Background Postpartum haemorrhage (PPH) is a major cause of maternal morbidity and one of the leading causes of maternal mortality worldwide. Many medical treatments and interventions are available nowadays, but surgical treatment is sometimes required when less invasive methods are unsuccessful. This study aimed to assess the theoretical and practical knowledge of French residents of Obstetrics and Gynecology concerning the surgical treatment of postpartum haemorrhage. Study design We performed a questionnaire study for senior residents of Obstetrics and Gynecology in France (fourth and fifth year of training). An anonymous survey was sent by email. Between December 2013 and April 2014, a total of 370 residents responded. Result The response rate was 47.6% (176/370). Only 156 questionnaires were fully completed and included for analysis. In all, 74% (115/156) of residents reported not mastering sufficiently or at all the technique for bilateral ligation of uterine arteries, 79% (123/156) for uterine compression sutures, 95% (148/156) for ligation of the internal iliac arteries, and 78% (122/156) for emergency peripartum hysterectomy. More than half of respondents (55%, 86/156) stated that they had not mastered any of these techniques. Conclusion An alarmingly high number of French senior residents in Obstetrics and Gynecology report that they have not acquired the sufficient surgical skills during their training to be able to perform the surgeries required for the management of PPH. Electronic supplementary material The online version of this article (10.1186/s12884-019-2237-3) contains supplementary material, which is available to authorized users.
Europe PubMed Centra... arrow_drop_down add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1186/s12884-019-2237-3&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu13 citations 13 popularity Top 10% influence Average impulse Top 10% Powered by BIP!
more_vert Europe PubMed Centra... arrow_drop_down add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1186/s12884-019-2237-3&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2018Heighten Science Publications Corporation Marwan O. Jalambo; Basil Kanoa; Mohammed S. Ellulu; Smaher Younis; Mueen El-Kariri;New Insights in Obes... arrow_drop_down add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.29328/journal.niogb.1001009&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!
more_vert New Insights in Obes... arrow_drop_down add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.29328/journal.niogb.1001009&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2013 United Kingdom, Netherlands, Italy, IrelandSpringer Science and Business Media LLC EC | COGS, NIH | Genetic epidemiology of c..., NIH | Breast &prostate cancer &... +6 projectsEC| COGS ,NIH| Genetic epidemiology of cell division regulation in breast cancer ,NIH| Breast &prostate cancer &hormone-related gene variants ,CIHR ,NIH| Characterizing Genetic Susceptibility to Breast and Prostate Cancer;the BPC3 ,NIH| Discovery Expansion and Replication ,NIH| Characterizing Genetic Susceptibility to Breast and Prostate Cancer: The BPC3. ,NIH| Breast &Prostate Cancer &Hormone-related Gene Variants ,WTAuthors: Montserrat Garcia-Closas; Sara Lindström; Kyriaki Michailidou; Marjanka K. Schmidt; +215 AuthorsMontserrat Garcia-Closas; Sara Lindström; Kyriaki Michailidou; Marjanka K. Schmidt; Mark N. Brook; Nick Orr; Suhn K. Rhie; Elio Riboli; Loic Le Marchand; Julie E. Buring; Diana Eccles; Peter A. Fasching; Hiltrud Brauch; Jenny Chang-Claude; Andrew K. Godwin; Heli Nevanlinna; Graham G. Giles; Angela Cox; John L. Hopper; Manjeet K. Bolla; Qin Wang; Joe Dennis; Ed Dicks; Nils Schoof; Stig E. Bojesen; Diether Lambrechts; Annegien Broeks; Irene L. Andrulis; Pascal Guénel; Barbara Burwinkel; Antoinette Hollestelle; Olivia Fletcher; Robert Winqvist; Hermann Brenner; Arto Mannermaa; Ute Hamann; Alfons Meindl; Peter Devillee; Jan Lubinski; Vessela N. Kristensen; Anthony J. Swerdlow; Thilo Dörk; Keitaro Matsuo; Anna H. Wu; Paolo Radice; William Blot; Daehee Kang; Mikael Hartman; Suleeporn Sangrajrang; Chen-Yang Shen; Melissa C. Southey; Daniel J. Park; Fleur Hammet; Jennifer Stone; Sarah Stewart-Brown; Pornthep Siriwanarangsan; Julian Peto; Michael G. Schrauder; Arif B. Ekici; Matthias W. Beckmann; Isabel dos Santos Silva; Nichola Johnson; Helen R. Warren; Ian Tomlinson; Michael J. Kerin; Nicola Miller; Federick Marme; Christof Sohn; Thérèse Truong; Pierre Laurent-Puig; Pierre Kerbrat; Børge G. Nordestgaard; Sune F. Nielsen; Henrik Flyger; Roger L. Milne; Jose Ignacio Arias Perez; Primitiva Menéndez; Heiko Müller; Christa Stegmaier; Magdalena Lochmann; Christina Justenhoven; Yon Ko; Taru A. Muranen; Kristiina Aittomäki; Carl Blomqvist; Dario Greco; Tuomas Heikkinen; Hidemi Ito; Hiroji Iwata; Yasushi Yatabe; Natalia Antonenkova; Sara Margolin; Vesa Kataja; Jaana M. Hartikainen; Rosemary L. Balleine; David Van Den Berg; Patrick Neven; Anne Sophie Dieudonne; Karin Leunen; Anja Rudolph; Dieter Flesch-Janys; Paolo Peterlongo; Bernard Peissel; Loris Bernard; Janet E. Olson; Xianshu Wang; Kristen N. Stevens; Gianluca Severi; Laura Baglietto; Catriona McLean; Gerhard A. Coetzee; Ye Feng; Brian E. Henderson; Fredrick R. Schumacher; Natalia Bogdanova; Martine Dumont; Cheng Har Yip; Nur Aishah Taib; Ching-Yu Cheng; Martha J. Shrubsole; Jirong Long; Katri Pylkäs; Arja Jukkola-Vuorinen; Julia A. Knight; Gord Glendon; Anna Marie Mulligan; R.A.E.M. Tollenaar; Mieke Kriege; Maartje J. Hooning; Carolien H.M. van Deurzen; Wei Lu; Hui Cai; Sabapathy P. Balasubramanian; Simon S. Cross; Malcolm W.R. Reed; Hui Miao; Ching Wan Chan; Anna Jakubowska; Katarzyna Jaworska; Katarzyna Durda; Chia-Ni Hsiung; Pei Ei Wu; Alan Ashworth; Michael Jones; Daniel C. Tessier; Anna González-Neira; Guillermo Pita; M. Rosario Alonso; Daniel Vincent; Francois Bacot; Christine B. Ambrosone; Elisa V. Bandera; Esther M. John; Gary K. Chen; Jennifer J. Hu; Jorge L. Rodriguez-Gil; Michael F. Press; Sandra Deming-Halverson; Sarah J. Nyante; Sue A. Ingles; Quinten Waisfisz; Enes Makalic; Daniel F. Schmidt; Minh Bui; Lorna Gibson; Bertram Müller-Myhsok; Rita K. Schmutzler; Rebecca Hein; Norbert Dahmen; Lars Beckmann; Kamila Czene; Astrid Irwanto; Jianjun Liu; Clare Turnbull; Nazneen Rahman; Hanne Meijers-Heijboer; Fernando Rivadeneira; Curtis Olswold; Susan L. Slager; Robert Pilarski; Foluso O. Ademuyiwa; Irene Konstantopoulou; Nicholas G. Martin; Grant W. Montgomery; Dennis J. Slamon; Claudia Rauh; Michael P. Lux; Sebastian M. Jud; Thomas Brüning; JoEllen Weaver; Priyanka Sharma; Harsh B. Pathak; William J. Tapper; Lorraine Durcan; Rosario Tumino; Petra H.M. Peeters; Federico Canzian; Elisabete Weiderpass; Mattias Johansson; Kay-Tee Khaw; Laurence N. Kolonel; Constance Chen; Andrew H. Beck; Susan E. Hankinson; Christine D. Berg; Robert N. Hoover; Jolanta Lissowska; Jonine D. Figueroa; Daniel I. Chasman; Mia M. Gaudet; David J. Hunter; Jacques Simard; Javier Benitez; Alison M. Dunning; Mark E. Sherman; Georgia Chenevix-Trench; Stephen J. Chanock; Christopher A. Haiman; Peter Kraft;Estrogen receptor (ER)-negative tumors represent 20-30% of all breast cancers, with a higher proportion occurring in younger women and women of African ancestry. The etiology and clinical behavior of ER-negative tumors are different from those of tumors expressing ER (ER positive), including differences in genetic predisposition. To identify susceptibility loci specific to ER-negative disease, we combined in a metaanalysis 3 genome-wide association studies of 4,193 ER-negative breast cancer cases and 35,194 controls with a series of 40 follow-up studies (6,514 cases and 41,455 controls), genotyped using a custom Illumina array, iCOGS, developed by the Collaborative Oncological Gene-environment Study (COGS). SNPs at four loci, 1q32.1 (MDM4, P= 2.1 x 10(-12) and LGR6, P = 1.4 x 10(-8)), 2p24.1 (P = 4.6 x 10(-8)) and 16q12.2 (FTO, P = 4.0 x 10(-8)), were associated with ER-negative but not ER-positive breast cancer (P> 0.05). These findings provide further evidence for distinct etiological pathways associated with invasive ER-positive and ER-negative breast cancers.
CORE (RIOXX-UK Aggre... arrow_drop_down Nature Genetics; Oxford University Research Archive; NARCISOther literature type . Article . 2013 . 2016License: http://www.springer.com/tdmArchivio della Ricerca - Università di PisaArticle . 2013Data sources: Archivio della Ricerca - Università di Pisaadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eu398 citations 398 popularity Top 1% influence Top 1% impulse Top 0.1% Powered by BIP!
visibility 13visibility views 13 download downloads 125 Powered bymore_vert CORE (RIOXX-UK Aggre... arrow_drop_down Nature Genetics; Oxford University Research Archive; NARCISOther literature type . Article . 2013 . 2016License: http://www.springer.com/tdmArchivio della Ricerca - Università di PisaArticle . 2013Data sources: Archivio della Ricerca - Università di Pisaadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Preprint 2014Embargo end date: 01 Jan 2014arXiv NSF | Collaborative Research: B..., NSF | Collaborative Research: B..., NSF | Collaborative Research: B... +1 projectsNSF| Collaborative Research: BICEP2 and SPUD - A Search for Inflation with Degree-Scale Polarimetry from the South Pole ,NSF| Collaborative Research: BICEP2 and SPUD - A Search for Inflation with Degree-Scale Polarimetry from the South Pole ,NSF| Collaborative Research: BICEP2 and SPUD - A Search for Inflation with Degree-Scale Polarimetry from the South Pole ,NSF| Collaborative Research: BICEP2 and SPUD - A Search for Inflation with Degree-Scale Polarimetry from the South PoleAde, P. A. R; Aikin, R. W.; Barkats, D.; Benton, S. J.; Bischoff, C. A.; Bock, J. J.; Brevik, J. A.; Buder, I.; Bullock, E.; Dowell, C. D.; Duband, L.; Filippini, J. P.; Fliescher, S.; Golwala, S. R.; Halpern, M.; Hasselfield, M.; Hildebrandt, S. R.; Hilton, G. C.; Hristov, V. V.; Irwin, K. D.; Karkare, K. S.; Kaufman, J. P.; Keating, B. G.; Kernasovskiy, S. A.; Kovac, J. M.; Kuo, C. L.; Leitch, E. M.; Lueker, M.; Mason, P.; Netterfield, C. B.; Nguyen, H. T.; O'Brient, R.; Ogburn, R. W.; Orlando, A.; Pryke, C.; Reintsema, C. D.; Richter, S.; Schwarz, R.; Sheehy, C. D.; Staniszewski, Z. K.; Sudiwala, R. V.; Teply, G. P.; Tolan, J. E.; Turner, A. D.; Vieregg, A. G.; Wong, C. L.; Yoon, K. W.;(abridged for arXiv) We report results from the BICEP2 experiment, a cosmic microwave background (CMB) polarimeter specifically designed to search for the signal of inflationary gravitational waves in the B-mode power spectrum around $\ell\sim80$. The telescope comprised a 26 cm aperture all-cold refracting optical system equipped with a focal plane of 512 antenna coupled transition edge sensor 150 GHz bolometers each with temperature sensitivity of $\approx300\mu\mathrm{K}_\mathrm{CMB}\sqrt{s}$. BICEP2 observed from the South Pole for three seasons from 2010 to 2012. A low-foreground region of sky with an effective area of 380 square deg was observed to a depth of 87 nK deg in Stokes $Q$ and $U$. We find an excess of $B$-mode power over the base lensed-LCDM expectation in the range $30 5\sigma$. Through jackknife tests and simulations we show that systematic contamination is much smaller than the observed excess. We also examine a number of available models of polarized dust emission and find that at their default parameter values they predict power $\sim(5-10)\times$ smaller than the observed excess signal. However, these models are not sufficiently constrained to exclude the possibility of dust emission bright enough to explain the entire excess signal. Cross correlating BICEP2 against 100 GHz maps from the BICEP1 experiment, the excess signal is confirmed and its spectral index is found to be consistent with that of the CMB, disfavoring dust at $1.7\sigma$. The observed $B$-mode power spectrum is well fit by a lensed-LCDM + tensor theoretical model with tensor-to-scalar ratio $r=0.20^{+0.07}_{-0.05}$, with $r=0$ disfavored at $7.0\sigma$. Accounting for the contribution of foreground dust will shift this value downward by an amount which will be better constrained with upcoming data sets. Comment: 26 pages, 14 figures
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Other literature type , Article 2018 Germany EnglishKarlsruhe EC | IS-ENES, EC | CALIPSOplus, NSF | Data Handling and Analysi... +6 projectsEC| IS-ENES ,EC| CALIPSOplus ,NSF| Data Handling and Analysis Infrastructure for Gravitational-wave Astronomy ,EC| CORBEL ,EC| AARC2 ,EC| EOSC-hub ,EC| GN4-2 ,EC| ELIXIR-EXCELERATE ,EC| IS-ENES2Atherton, Christopher John; Barton, Thomas; Basney, Jim; Broeder, Daan; Costa, Alessandro; Daalen, Mirjam Van; Dyke, Stephanie; Elbers, Willem; Enell, Carl-Fredrik; Fasanelli, Enrico Maria Vincenzo; Fernandes, João; Florio, Licia; Gietz, Peter; Groep, David L.; Junker, Matthias Bernhard; Kanellopoulos, Christos; Kelsey, David; Kershaw, Philip; Knapic, Cristina; Kollegger, Thorsten; Koranda, Scott; Linden, Mikael; Marinic, Filip; Matyska, Ludek; Nyrönen, Tommi Henrik; Paetow, Stefan; Paglione, Laura A D; Parlati, Sandra; Phillips, Christopher; Prochazka, Michal; Rees, Nicholas; Short, Hannah; Stevanovic, Uros; Tartakovsky, Michael; Venekamp, Gerben; Vitez, Tom; Wartel, Romain; Whalen, Christopher; White, John; Zwölf, Carlo Maria;The authors also acknowledge the support and collaboration of many other colleagues in their respective institutes, research communities and IT Infrastructures, together with the funding received by these from many different sources. These include but are not limited to the following: (i) The Worldwide LHC Computing Grid (WLCG) project is a global collaboration of more than 170 computing centres in 43 countries, linking up national and international grid infrastructures. Funding is acknowledged from many national funding bodies and we acknowledge the support of several operational infrastructures including EGI, OSG and NDGF/NeIC. (ii) EGI acknowledges the funding and support received from the European Commission and the many National Grid Initiatives and other members. EOSC-hub receives funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 777536. (iii) The work leading to these results has received funding from the European Union's Horizon 2020 research and innovation programme under Grant Agreement No. 730941 (AARC2). (iv) Work on the development of ESGF's identity management system has been supported by The UK Natural Environment Research Council and funding from the European Union's Seventh Framework Programme for research, technological development and demonstration through projects IS-ENES (grant agreement no 228203) and IS-ENES2 (grant agreement no 312979). (v) Ludek Matyska and Michal Prochazka acknowledge funding from the RI ELIXIR CZ project funded by MEYS Czech Republic No. LM2015047. (vi) Scott Koranda acknowledges support provided by the United States National Science Foundation under Grant No. PHY-1700765. (vii) GÉANT Association on behalf of the GN4 Phase 2 project (GN4-2).The research leading to these results has received funding from the European Union's Horizon 2020 research and innovation programme under Grant Agreement No. 731122(GN4-2). (viii) ELIXIR acknowledges support from Research Infrastructure programme of Horizon 2020 grant No 676559 EXCELERATE. (ix) CORBEL life science cluster acknowledges support from Horizon 2020 research and innovation programme under grant agreement No 654248. (x) Mirjam van Daalen acknowledges that the research leading to this result has been supported by the project CALIPSOplus under the Grant Agreement 730872 from the EU Framework Programme for Research and Innovation HORIZON 2020. (xi) EISCAT is an international association supported by research organisations in China (CRIRP), Finland (SA), Japan (NIPR), Norway (NFR), Sweden (VR), and the United Kingdom (NERC). This white-paper expresses common requirements of Research Communities seeking to leverage Identity Federation for Authentication and Authorisation. Recommendations are made to Stakeholders to guide the future evolution of Federated Identity Management in a direction that better satisfies research use cases. The authors represent research communities, Research Services, Infrastructures, Identity Federations and Interfederations, with a joint motivation to ease collaboration for distributed researchers. The content has been edited collaboratively by the Federated Identity Management for Research (FIM4R) Community, with input sought at conferences and meetings in Europe, Asia and North America.
https://doi.org/10.5... arrow_drop_down ZENODOOther literature type . Article . 2018add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eu17 citations 17 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert https://doi.org/10.5... arrow_drop_down ZENODOOther literature type . Article . 2018add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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description Publicationkeyboard_double_arrow_right Preprint , Article , Other literature type 2018 FranceCopernicus GmbH SNSF | Volcanic Eruptions and th..., SNSF | Future and Past Solar Inf..., EC | STRATOCLIM +1 projectsSNSF| Volcanic Eruptions and their impact on future Climate (VEC) ,SNSF| Future and Past Solar Influence on the Terrestrial Climate II ,EC| STRATOCLIM ,SNSF| Study to determine Spectral Solar Irradiance and its impact on the middle atmosphere (SIMA)Kévin Lamy; Thierry Portafaix; Béatrice Josse; Colette Brogniez; Sophie Godin-Beekmann; Hassan Bencherif; Laura E. Revell; Hideharu Akiyoshi; Slimane Bekki; Michaela I. Hegglin; Patrick Jöckel; Oliver Kirner; Virginie Marécal; Olaf Morgenstern; Andrea Stenke; Guang Zeng; N. Luke Abraham; Alexander T. Archibald; N. Butchart; Martyn P. Chipperfield; Glauco Di Genova; Makoto Deushi; Sandip Dhomse; Rong-Ming Hu; Douglas E. Kinnison; Martine Michou; Fiona M. O'Connor; Luke D. Oman; Giovanni Pitari; David A. Plummer; John A. Pyle; Eugene Rozanov; David Saint-Martin; Kengo Sudo; Taichu Tanaka; Daniele Visioni; Kohei Yoshida;We have derived values of the Ultraviolet Index (UVI) at solar noon using the Tropospheric Ultraviolet Model (TUV) driven by ozone, temperature and aerosol fields from climate simulations of the first phase of the Chemistry-Climate Model Initiative (CCMI-1). Since clouds remain one of the largest uncertainties in climate projections, we simulated only the clear-sky UVI. We compared the modelled UVI climatologies against present-day climatological values of UVI derived from both satellite data (the OMI-Aura OMUVBd product) and ground-based measurements (from the NDACC network). Depending on the region, relative differences between the UVI obtained from CCMI/TUV calculations and the ground-based measurements ranged between −5.9% and 10.6%. We then calculated the UVI evolution throughout the 21st century for the four Representative Concentration Pathways (RCPs 2.6, 4.5, 6.0 and 8.5). Compared to 1960s values, we found an average increase in the UVI in 2100 (of 2–4%) in the tropical belt (30°N-30°S). For the mid-latitudes, we observed a 1.8 to 3.4 % increase in the Southern Hemisphere for RCP 2.6, 4.5 and 6.0, and found a 2.3% decrease in RCP 8.5. Higher increases in UVI are projected in the Northern Hemisphere except for RCP 8.5. At high latitudes, ozone recovery is well identified and induces a complete return of mean UVI levels to 1960 values for RCP 8.5 in the Southern Hemisphere. In the Northern Hemisphere, UVI levels in 2100 are higher by 0.5 to 5.5% for RCP 2.6, 4.5 and 6.0 and they are lower by 7.9% for RCP 8.5. We analysed the impacts of greenhouse gases (GHGs) and ozone-depleting substances (ODSs) on UVI from 1960 by comparing CCMI sensitivity simulations (1960–2100) with fixed GHGs or ODSs at their respective 1960 levels. As expected with ODS fixed at their 1960 levels, there is no large decrease in ozone levels and consequently no sudden increase in UVI levels. With fixed GHG, we observed a delayed return of ozone to 1960 values, with a corresponding pattern of change observed on UVI, and looking at the UVI difference between 2090s values and 1960s values, we found an 8 % increase in the tropical belt during the summer of each hemisphere. Finally we show that, while in the Southern Hemisphere the UVI is mainly driven by total ozone column, in the Northern Hemisphere both total ozone column and aerosol optical depth drive UVI levels, with aerosol optical depth having twice as much influence on the UVI as total ozone column does.
https://doi.org/10.5... arrow_drop_down HAL Descartes; HAL-Pasteur; HAL-InsermArticle . 2018add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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