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Additional file 1 of Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study
NIH| DIET, HORMONES AND RISK OF COLORECTAL CANCERS ,
NIH| Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health Study ,
EC| TICE ,
NIH| GWAS Identified Colorectal Cancer SNPs and Colorectal Polyp Risk ,
NIH| EARLY CANCER DETECTION AND SUSCEPTIBILITY BIOMAKERS ,
NIH| Genome Wide Association Coordinating Center ,
WT ,
NIH| Institute of Translational Health Sciences ,
NIH| The Epidemiology of Immune Responses in Colorectal Cancer ,
NIH| Diet, Genetic Susceptibility and Colorectal Neoplasia ,
NIH| MOFFITT CANCER CENTER SUPPORT GRANT ,
NHMRC| Risk factors for molecular sub-types of colorectal cancer ,
CIHR ,
NIH| Research Program: Gastrointestinal Cancer ,
UKRI| Health of vegetarians ,
NIH| Epigenetic Events and Colorectal Cancer Epidemiology ,
NHMRC| Risk and prognostic factors for breast cancer of different immunohistochemical subtypes ,
NIH| Population Study of Rectal Cancer in Blacks and Whites ,
NIH| SOUTHWEST ONCOLOGY GROUP -- CCOP RESARCH BASE ,
NIH| Lifestyle, genetics and colonoscopy for colorectal cancer prevention ,
UKRI| Causal analyses, statistical efficiency and phenotypic precision through study design: Genotype based sampling ,
NIH| NUTRITIONAL AND BIOCHEMICAL MARKERS OF CANCER AND MI ,
WT| The Avon Longitudinal Study of Parents and Children (ALSPAC): A multi-generation, longitudinal resource focusing on life course health and well-being. ,
NIH| Colon Cancer Family Registry Cohort ,
NIH| GENETIC EPIDEMIOLOGIC STUDIES OF COLON POLYPS AND CANCER ,
NIH| CORE--CELL CULTURE FACILITY ,
NIH| Molecular pathological epidemiology of colorectal cancer ,
NIH| Discovery and verification of novel biomarkers of colorectal cancer recurrence ,
NIH| Genomic Wide Association Study of Colorectal Cancer ,
NIH| AROMATIC AMINES AND COLON CANCER RISK--GENETICS ,
NIH| Understanding Ethnic Differences in Cancer: The Multiethnic Cohort Study ,
NIH| Statistical Methods for Integrative Genomics in Cancer ,
NIH| PROSPECTIVE STUDY OF DIET AND CANCER IN MEN (HEALTH PROFESSIONALS FOLLOWUP) ,
NIH| JH/CIDR Genotyping for Genome-Wide Association Studies ,
NIH| Inflammation and Colorectal Neoplasia ,
NIH| Enhancing the PCPT/SELECT cohorts Core Infrastructure Grant to support studies evaluating dietary supplement use and disease risk ,
WT| What lies behind the causal impact of body mass index (BMI) level and change on human health? Added value from complementary study design and deep metabolomic phenotyping. ,
NIH| Established Investigator Award Anti-Inflammatory Exposures in Cancer Prevention ,
NIH| Cancer Epidemiology Cohort in Male Health Professionals ,
NHMRC| Epidemiology of Chronic Disease, Health Interventions and DNA Studies ,
NIH| Training Grant in Genomic Analysis and Interpretation ,
NIH| The Colon Cancer Family Registry: Ontario ,
NIH| CLUE STUDIES--EVALUATING BIOMARKERS OF CARCINOGENESIS ,
NIH| Diet, Activity, and Lifestyle as a Risk Factor for Colorectal Cancer ,
NIH| EPIDEMIOLOGIC STUDIES OF DIET AND CANCER HAWAII ,
EC| PREVIEW ,
NIH| A Whole Genome Admixture Scan For Prostate Cancer Genes ,
NIH| Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare Study ,
UKRI| Mendelian randomization to hypothesis-free causal inference ,
NIH| Regional Oncology Research Center ,
NIH| Tissue and Pathology Resources ,
NIH| Multiethnic Cohort Study of Diet and Cancer ,
NIH| Detection of Colorectal Cancer Susceptibility Loci Using Genome-Wide Sequencing ,
WT| Institutional Strategic Support Fund ,
NIH| Hormones and Colon Cancer: Epigenetic Subtypes, Risk, and Survival ,
NIH| Metabolomic Strategies for Discovery and Validation of Biomarkers of Colorectal Cancer Recurrence ,
NIH| MOLECULAR EPIDEMIOLOGY OF COLORECTAL CANCER ,
NIH| Cancer Survivorship: Decreasing the Risk of Colon Cancer Mortality ,
NIH| Obesity-Related Insulin Resistance Signaling Pathway Factors and Colon Cancer ,
NIH| Using Functional Data to Reveal Gene-Environment Interaction in Colorectal Cancer ,
NIH| Ontario Registry for Studies of Familial Colon Cancer ,
NIH| Administrative Core and Enrichment Program ,
NIH| Accelerating Transdisciplinary Epidemiology of Colorectal Cancer ,
NIH| Epidemiologic Studies ,
NIH| The Colon Cancer Family Registry: Seattle ,
NIH| Colon Cancer Pathways: Hyperplastic Polyps and Adenomas ,
NIH| GENE-ENVIRONMENT INTERACTIONS: THE ODYSSEY COHORT ,
NIH| USC COMPREHENSIVE CANCER CENTER (CORE) SUPPORT ,
NIH| Using functional genomics to inform gene environment interactions for colorectal cancer
Bull, Caroline J.; Bell, Joshua A.; Murphy, Neil; Sanderson, Eleanor; Smith, George Davey; Timpson, Nicholas J.; Banbury, Barbara L.; +71 Authors
Bull, Caroline J.; Bell, Joshua A.; Murphy, Neil; Sanderson, Eleanor; Smith, George Davey; Timpson, Nicholas J.; Banbury, Barbara L.; Albanes, Demetrius; Berndt, Sonja I.; Bézieau, Stéphane; D. Timothy Bishop; Brenner, Hermann; Buchanan, Daniel D.; Burnett-Hartman, Andrea; Casey, Graham; Castellví-Bel, Sergi; Chan, Andrew T.; Chang-Claude, Jenny; Cross, Amanda J.; Chapelle, Albert De La; Figueiredo, Jane C.; Gallinger, Steven J.; Gapstur, Susan M.; Giles, Graham G.; Gruber, Stephen B.; Gsur, Andrea; Hampe, Jochen; Hampel, Heather; Harrison, Tabitha A.; Hoffmeister, Michael; Hsu, Li; Huang, Wen-Yi; Huyghe, Jeroen R.; Jenkins, Mark A.; Joshu, Corinne E.; Temitope O. Keku; Kühn, Tilman; Sun-Seog Kweon; Loic Le Marchand; Li, Christopher I.; Li, Li; Lindblom, Annika; Martín, Vicente; May, Anne M.; Milne, Roger L.; Moreno, Victor; Newcomb, Polly A.; Offit, Kenneth; Ogino, Shuji; Phipps, Amanda I.; Platz, Elizabeth A.; Potter, John D.; Conghui Qu; J. Ramón Quirós; Rennert, Gad; Riboli, Elio; Sakoda, Lori C.; Schafmayer, Clemens; Schoen, Robert E.; Slattery, Martha L.; Tangen, Catherine M.; Tsilidis, Kostas K.; Ulrich, Cornelia M.; Fränzel J. B. Van Duijnhoven; Guelpen, Bethany Van; Visvanathan, Kala; Vodicka, Pavel; Vodickova, Ludmila; Hansong Wang; White, Emily; Wolk, Alicja; Woods, Michael O.; Wu, Anna H.; Campbell, Peter T.; Zheng, Wei; Peters, Ulrike; Vincent, Emma E.; Gunter, Marc J.;
Additional file 1 of Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study
Additional file 1: Table S1. Genetic variants used to instrument BMI, WHR and metabolites. Table S2. Assesment of instrument strength. Table S3. Colorectal cancer case distributions by study, sex and site. Table S4. LogOR colorectal cancer per SD higher BMI or WHR. Table S5. Beta change in NMR-detected metabolite per SD higher BMI or WHR. Table S6. LogOR colorectal cancer per SD higher BMI or WHR-driven NMR-detected metabolite. Table S7. Risk of overall colorectal cancer per SD higher adipose or metabolite trait, estimated using multivariable Mendelian randomization. Table S8. Posthoc investigations.
Medical Subject Headings: nutritional and metabolic diseases
Medical Subject Headings: nutritional and metabolic diseases
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citations
Citations provided by BIP!
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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Funded byView all
NIH| DIET, HORMONES AND RISK OF COLORECTAL CANCERS, NIH| Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health Study, EC| TICE
Project
- National Institutes of Health (NIH)
- 3P01CA087969-03S1
- NATIONAL CANCER INSTITUTE
Project
- National Institutes of Health (NIH)
- 5UM1CA186107-05
- NATIONAL CANCER INSTITUTE
, NIH| GWAS Identified Colorectal Cancer SNPs and Colorectal Polyp Risk
Project
- National Institutes of Health (NIH)
- 5R03CA153323-02
- NATIONAL CANCER INSTITUTE
Related to Research communities
Additional file 1: Table S1. Genetic variants used to instrument BMI, WHR and metabolites. Table S2. Assesment of instrument strength. Table S3. Colorectal cancer case distributions by study, sex and site. Table S4. LogOR colorectal cancer per SD higher BMI or WHR. Table S5. Beta change in NMR-detected metabolite per SD higher BMI or WHR. Table S6. LogOR colorectal cancer per SD higher BMI or WHR-driven NMR-detected metabolite. Table S7. Risk of overall colorectal cancer per SD higher adipose or metabolite trait, estimated using multivariable Mendelian randomization. Table S8. Posthoc investigations.