research data . Dataset . 2014

Supplementary Material for: Longitudinal Effects of Metabolic Syndrome on Alzheimer and Vascular Related Brain Pathology

Lin, F.; Lo, R.Y.; Cole, D.; Ducharme, S.; Chen, D.-G.; Mapstone, M.; Porsteinsson, A.;
Open Access
  • Published: 01 Jan 2014
  • Publisher: Karger Publishers
Abstract
Background/Aims: This study examines the longitudinal effect of metabolic syndrome (MetS) on brain-aging indices among cognitively normal (CN) and amnestic mild cognitive impairment (aMCI) groups [single-domain aMCI (saMCI) and multiple-domain aMCI (maMCI)]. Methods: The study population included 739 participants (CN = 226, saMCI = 275, and maMCI = 238) from the Alzheimer's Disease Neuroimaging Initiative, a clinic-based, multi-center prospective cohort. Confirmatory factor analysis was employed to determine a MetS latent composite score using baseline data of vascular risk factors. We examined the changes of two Alzheimer's disease (AD) biomarkers, namely [18F]...
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Funded by
CIHR
Project
  • Funder: Canadian Institutes of Health Research (CIHR)
,
NIH| The University of Rochester Clinical and Translational Science Institute
Project
  • Funder: National Institutes of Health (NIH)
  • Project Code: 5KL2TR000095-09
  • Funding stream: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES
,
NIH| Alzheimers Disease Neuroimaging Initiative
Project
  • Funder: National Institutes of Health (NIH)
  • Project Code: 1U01AG024904-01
  • Funding stream: NATIONAL INSTITUTE ON AGING
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Dataset . 2014
Provider: Datacite
Open Access
figshare
Dataset . 2014
Provider: Datacite
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