G protein-coupled receptors (GPCRs) represent the largest family of cell surface proteins. Agonist binding to GPCRs activates G proteins regulating many cellular effectors. Classically, G protein activation occurs at the plasma membrane and is rapidly terminated by β-ar...

The origin of oxygenic photosynthesis is one of the most dramatic evolutionary events that the Earth has ever experienced. At some point in Earth’s first two billion years, primitive bacteria acquired the ability to harness sunlight, oxidize water, release O2, and trans...