Background: Data are limited on whether clinical trials have randomized higher-risk patients over time and how trends in risk profiles and evidence-based pharmacotherapies have influenced trial outcomes. We quantified changes in baseline risk, treatment, and outcomes of...

Stacked bar charts are a visualization method for presenting multiple attributes of data, and many visualization tools support these charts. To assess the efficacy of stacked bar charts in supporting attribute-comparison tasks, we conducted a user study to compare three...

spinal cord injuries (mobility: 0.61, 95%CI 0.45,0.83), self-care: 0.76, 95%CI 0.63,0.91, activity: 0.64, 95%CI 0.47,0.88)

Abstract Background In this field study of WHO's revised classification of mental disorders for primary care settings, the ICD-11 PHC, we tested the usefulness of two five-item screening scales for anxiety and depression to be administered in primary care settings. Meth...

Successful mass drug administration (MDA) campaigns have brought several countries near the point of Lymphatic Filariasis (LF) elimination. A diagnostic tool is needed to determine when the prevalence levels have decreased to a point that MDA campaigns can be discontinu...

Measurements are presented of increased harmonic currents in a 500 kV power system due to geomagnetically induced currents (GIC). The measurements were made of 60 Hz, 120 Hz, and 180 Hz currents and GIC in a 1200 MVA transformer. The recorded increases in the harmonic c...

BACKGROUND: Alfalfa has the disadvantage of having a rapid initial rate of protein degradation, which results in pasture bloat, low efficiency of protein utilisation and excessive nitrogen (N) pollution into the environment for cattle. Introducing a gene that stimulates...

In the present study, we explored the real-world efficacy of the immuno-oncology checkpoint inhibitor nivolumab and the tyrosine kinase inhibitor cabozantinib in the second-line setting. Using the International Metastatic Renal Cell Carcinoma Database Consortium (imdc) ...

The authors argue that UNCITRAL Working Group III, as part of its mandate for reform of the international investment regime, should consider issues at the core of the concerns about the regime's accountability and legitimacy, especially in the case of investor-state dis...