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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: D. D. Maharaj; Gabriele Sala; Casey Marjerrison; Matthew B. Stone; +2 Authors

    Time-of-flight inelastic neutron scattering measurements have been carried out on polycrystalline samples of the $4{d}^{3}$ and $5{d}^{3}$ double pervoskite antiferromagnets ${\mathrm{La}}_{2}{\mathrm{LiRuO}}_{6}$ and ${\mathrm{La}}_{2}{\mathrm{LiOsO}}_{6}$. These reveal the development of an inelastic spin gap in ${\mathrm{La}}_{2}{\mathrm{LiRuO}}_{6}$ and ${\mathrm{La}}_{2}{\mathrm{LiOsO}}_{6}$ of $\ensuremath{\sim}1.8(8)$ and 6(1) meV, below their respective ordering temperatures ${T}_{N},\phantom{\rule{0.28em}{0ex}}\ensuremath{\sim}23.8$ and 30 K. The bandwidths of the spin excitations are shown to be $\ensuremath{\sim}5.7(9)\phantom{\rule{0.28em}{0ex}}\text{and}\phantom{\rule{0.28em}{0ex}}12(1)\phantom{\rule{0.28em}{0ex}}\mathrm{meV}$, respectively, at low temperatures. Spin gaps are surprising in such magnets as the ${t}_{2g}$ levels of ${\mathrm{Ru}}^{5+}$ or ${\mathrm{Os}}^{5+}$ are expected to be half-filled, resulting in an anticipated orbital singlet for both materials. We compare these results in monoclinic double perovskites ${\mathrm{La}}_{2}{\mathrm{LiRuO}}_{6}$ and ${\mathrm{La}}_{2}{\mathrm{LiOsO}}_{6}$ with those in cubic ${\mathrm{Ba}}_{2}{\mathrm{YRuO}}_{6}$ and ${\mathrm{Ba}}_{2}{\mathrm{YOsO}}_{6}$ as well as with those in other monoclinic ${\mathrm{La}}_{2}{\mathrm{NaRuO}}_{6},\phantom{\rule{0.28em}{0ex}}{\mathrm{La}}_{2}{\mathrm{NaOsO}}_{6}$, and ${\mathrm{Sr}}_{2}{\mathrm{ScOsO}}_{6}$ and model the inelastic magnetic scattering with linear spin-wave theory using minimal anisotropic exchange interactions. We discuss the possible role of the distortion of the face-centered-cubic double perovskite structure on the spin gap formation and geometric frustration in these materials and show that ${T}_{N}$ scales with the top of the spin-wave band in all members of these families that display long-range order.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ https://link.aps.org...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    https://doi.org/10.1103/physre...
    Article . 2018
    License: APS Licenses for Journal Article Re-use
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ https://link.aps.org...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      https://link.aps.org/accepted/...
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      image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
      https://doi.org/10.1103/physre...
      Article . 2018
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  • image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    Authors: Banyar Aung; Margaret Y. Gruber; Lisa Amyot; Khaled W. Omari; +2 Authors

    MicroRNA156 (miR156) is a regulator of flowering time and biomass production through regulation of members of SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) gene family. To expand our investigations on the utility of miR156 in alfalfa, we generated transgenic alfalfa expressing a heterologous miR156 from Lotus japonicus (LjmiR156a). 5′ RACE and qRT-PCR analysis confirmed that the same three SPL genes (MsSPL6, MsSPL12, and MsSPL13) targeted by MsmiR156d are also targets of LjmiR156a in alfalfa. Ectopic expression of LjmiR156a down-regulated these SPL genes in transgenic alfalfa, coupled with reduced internode length, a more extreme delay in flowering time than occurred with MsmiR156d, enhanced shoot branching, and elevated biomass production. While root length was maintained, nodulation was reduced in some transgenic genotypes. Furthermore, heterologous expression of LjmiR156a enhanced the contents of starch, soluble sugars, and phenolics in all transgenic genotypes in contrast to the impact from MsmiR156d enhancement, even though the effects on lignin, cellulose, pectin, structural sugars, flavonoids, and carotenoids were variable among the new alfalfa genotypes. The variations among the traits/genotypes reflect the change in expression of alfalfa SPL genes targeted by LjmiR156a and show that LjmiR156a could be employed as a tool to improve quality and yield of alfalfa biomass.

    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Plant Biotechnology ...arrow_drop_down
    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    Plant Biotechnology Reports
    Article . 2015
    License: Springer TDM
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      image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Plant Biotechnology ...arrow_drop_down
      image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
      Plant Biotechnology Reports
      Article . 2015
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Diganta Sarkar; Riley Hooper; Abhoy Karmakar; Victor Terskikh; +1 Authors

    We report a rapid solid−state 35/37Cl NMR strategy for 3D organic−inorganic hybrid and low−dimensional (2D and 0D) all−inorganic lead−based perovskites embracing ultra-wideline acquisition approaches and moderate to ultrahigh magnetic fields. The observed quadrupolar NMR parameters (CQ and η), supported by GIPAW−DFT computations, revealed distinct features for unique local Cl environments with the variation of the A−site and dimensionality. 35Cl CQ values display the potential for becoming an informative probe of distinct Cl chemical environments.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ https://doi.org/10.2...arrow_drop_down
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    https://doi.org/10.26434/chemr...
    Preprint . 2021
    License: CC BY NC ND
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    https://chemrxiv.org/engage/ap...
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ https://doi.org/10.2...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      https://doi.org/10.26434/chemr...
      Preprint . 2021
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      https://chemrxiv.org/engage/ap...
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: G A, Wood; D S, Sarma; M C, Archer;

    Previously, we have shown that Copenhagen (Cop) rats are highly resistant to the induction of putative preneoplastic, glutathione S-transferase 7-7 (GST 7-7)-positive liver lesions following treatment with a modified resistant hepatocyte protocol. The objective of the current study was to establish the time course for the development of resistance and examine potential resistance mechanisms in Cop rats using F344 rats as susceptible controls. Male Cop and F344 rats (n = 25), 7-8 weeks of age, were initiated with diethylnitrosamine (200 mg/kg) and promoted 3 weeks later with four doses of 2-acetylaminofluorene (20 mg/kg) and a 2/3 partial hepatectomy (PH). Groups of rats from each strain were killed on days 2, 4, 7, 14 and 21 post-PH, 2 h after receiving bromodeoxyuridine. Cop livers contained similar numbers of GST 7-7-positive lesions to F344 livers on days 2 and 4 post-PH. The percent volume of liver occupied by these lesions did not differ between the strains on days 2, 4 and 7 post-PH. On day 14, however, approximately 29% of the liver volume in F344 rats was occupied by lesions, whereas in Cop rats this was significantly less (approximately 9%, P0.001). On day 21, lesions occupied approximately 58% of F344 rat livers and only approximately 6% of Cop livers. Despite these differences, the labeling index of hepatocytes was not significantly different between the strains at any time point, either within lesions or within surrounding normal liver. Furthermore, the apoptotic indices were not different between the strains at any time. However, differences were found in the extent of lesion remodeling (redifferentiation) and in the pattern of oval cell response following PH in Cop livers. By day 14 post-PH, approximately 76% of Cop liver lesions showed evidence of remodeling, compared with only approximately 14% of F344 lesions. The oval cell response to PH was equivalent in the two strains up to day 4 post-PH but by day 7, in F344 livers there was extensive migration of these cells into the liver parenchyma, whereas in Cop livers, the response remained localized to the portal regions. These results suggest that Cop resistance occurs at the promotion stage and not the initiation stage of carcinogenesis. Resistance appears not to be due to a lower proliferation rate nor to a higher apoptotic rate within Cop lesions. Precocious remodeling and/or a diminished oval cell response, however, may contribute to the resistance of Cop rats to the growth of GST 7-7-positive hepatic lesions.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Carcinogenesisarrow_drop_down
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    Carcinogenesis
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    Carcinogenesis
    Article . 1999
    Carcinogenesis
    Article . 1999
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Carcinogenesisarrow_drop_down
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      Carcinogenesis
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      Carcinogenesis
      Article . 1999
      Carcinogenesis
      Article . 1999
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Gregory W. McGarr; Naoto Fujii; Madison D. Schmidt; Caroline M. Muia; +1 Authors

    Abstract Heat shock protein 90 (HSP90) modulates exercise‐induced cutaneous vasodilation in young men via nitric oxide synthase (NOS), but only when core temperature is elevated ~1.0°C. While less is known about modulation of this heat loss response in women during exercise, sex differences may exist. Further, the mechanisms regulating cutaneous vasodilation can differ between exercise‐ and passive‐heat stress. Therefore, in 11 young women (23 ± 3 years), we evaluated whether HSP90 contributes to NOS‐dependent cutaneous vasodilation during exercise (Protocol 1) and passive heating (Protocol 2) and directly compared responses between end‐exercise and a matched core temperature elevation during passive heating. Cutaneous vascular conductance (CVC%max) was measured at four forearm skin sites continuously treated with (a) lactated Ringers solution (control), (b) 178 μM Geldanamycin (HSP90 inhibitor), (c) 10 mM L‐NAME (NOS inhibitor), or (d) combined 178 μM Geldanamycin and 10 mM L‐NAME. Participants completed both protocols during the early follicular (low hormone) phase of the menstrual cycle (0–7 days). Protocol 1: participants rested in the heat (35°C) for 70 min and then performed 50 min of moderate‐intensity cycling (~55% VO2peak) followed by 30 min of recovery. Protocol 2: participants were passively heated to increase rectal temperature by 1.0°C, comparable to end‐exercise. HSP90 inhibition attenuated CVC%max relative to control at end‐exercise (p < .05), but not during passive heating. While NOS inhibition and combined HSP90 + NOS inhibition attenuated CVC%max relative to control for both protocols (all p < .05), they did not differ from each other. We show that HSP90 modulates cutaneous vasodilation NOS‐dependently during exercise in young women, with no effect during passive heating, despite a similar NOS contribution. We evaluated whether HSP90 contributes to NOS‐dependent cutaneous vasodilation during exercise and passive heating in young women. We directly compared these responses at end‐exercise and the matched core temperature elevation during passive heating. We showed that HSP90 modulates cutaneous vasodilation NOS‐dependently during exercise in young women, while there was no effect of HSP90 inhibition during passive heating, despite a similar NOS contribution.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Europe PubMed Centra...arrow_drop_down
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    Europe PubMed Central
    Article . 2020
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    Physiological Reports
    Article . 2020
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    Physiological Reports
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    DOAJ-Articles
    Article . 2020
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      Europe PubMed Central
      Article . 2020
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      Physiological Reports
      Article . 2020
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      Physiological Reports
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      DOAJ-Articles
      Article . 2020
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    Authors: Kob, Walter; Donati, Claudio; Plimpton, Steven J.; Poole, Peter H.; +1 Authors

    We present the results of a large scale molecular dynamics computer simulation study in which we investigate whether a supercooled Lennard-Jones liquid exhibits dynamical heterogeneities. We evaluate the non-Gaussian parameter for the self part of the van Hove correlation function and use it to identify ``mobile'' particles. We find that these particles form clusters whose size grows with decreasing temperature. We also find that the relaxation time of the mobile particles is significantly shorter than that of the bulk, and that this difference increases with decreasing temperature. Comment: 8 pages of RevTex, 4 ps figures

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    Physical Review Letters
    Article . 1997
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      Physical Review Letters
      Article . 1997
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    Authors: Frolov, V. P.; Fursaev, D. V.; Page, D. N.;

    We consider thorny spheres, that is 2-dimensional compact surfaces which are everywhere locally isometric to a round sphere $S^2$ except for a finite number of isolated points where they have conical singularities. We use thorny spheres to generate, from a spherically symmetric solution of the Einstein equations, new solutions which describe spacetimes pierced by an arbitrary number of infinitely thin cosmic strings radially directed. Each string produces an angle deficit proportional to its tension, while the metric outside the strings is a locally spherically symmetric solution. We prove that there can be arbitrary configurations of strings provided that the directions of the strings obey a certain equilibrium condition. In general this equilibrium condition can be written as a force-balance equation for string forces defined in a flat 3-space in which the thorny sphere is isometrically embedded, or as a constraint on the product of holonomies around strings in an alternative 3-space that is flat except for the strings. In the case of small string tensions, the constraint equation has the form of a linear relation between unit vectors directed along the string axes. 37 pages, 11 figures

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    https://doi.org/10.1103/physre...
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      https://doi.org/10.1103/physre...
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    Authors: Samei, Nasim; Solis-Oba, Roberto;

    In the constrained max k-cut problem on hypergraphs, we are given a weighted hypergraph H=(V, E), an integer k and a set c of constraints. The goal is to divide the set V of vertices into k disjoint partitions in such a way that the sum of the weights of the hyperedges having at least two endpoints in different partitions is maximized and the partitions satisfy all the constraints in c. In this paper we present a local search algorithm for the constrained max k-cut problem on hypergraphs and show that it has approximation ratio 1-1/k for a variety of constraints c, such as for the constraints defining the max Steiner k-cut problem, the max multiway cut problem and the max k-cut problem. We also show that our local search algorithm can be used on the max k-cut problem with given sizes of parts and on the capacitated max k-cut problem, and has approximation ratio 1-|Vmax|/|V|, where |Vmax| is the cardinality of the biggest partition. In addition, we present a local search algorithm for the directed max k-cut problem that has approximation ratio (k-1)/(3k-2).

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    Authors: Mohammadi, Alireza; Maggiore, Manfredi; Consolini, Luca;

    This article investigates the problem of enforcing a virtual holonomic constraint (VHC) on a mechanical system with degree of underactuation one while simultaneously stabilizing a closed orbit on the constraint manifold. This problem, which to date is open, arises when designing controllers to induce complex repetitive motions in robots. In this paper, we propose a solution which relies on the parameterization of the VHC by the output of a double-integrator. While the original control inputs are used to enforce the VHC, the control input of the double-integrator is designed to asymptotically stabilize the closed orbit and make the state of the double-integrator converge to zero. The proposed design is applied to the problem of making a PVTOL aircraft follow a circle on the vertical plane with a desired speed profile, while guaranteeing that the aircraft does not roll over for suitable initial conditions. Comment: Accepted for publication in Automatica

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    Automatica
    Article . 2018
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      Article . 2018
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  • image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    Authors: Robin A. Buckley; A. Guy Plint; Olivia A. Henderson; Jessica R. Krawetz; +1 Authors

    AbstractRegional mapping of Middle Albian, shallow‐marine clastic strata over ca 100 000 km2 of the Western Canada Foreland Basin was undertaken to investigate the relationship between large‐scale stratal architecture and lithology. Results suggest that, over ca 5 Myr, stratal geometry and facies were dynamically linked to tectonic activity in the adjacent Cordillera. Higher frequency modulation of accommodation is most reasonably ascribed to eustasy. The Harmon and Cadotte alloformations were deposited at the southern end of an embayment of the Arctic Ocean. The Harmon alloformation, forming the lower part of the succession, constitutes a wedge of marine mudstone that thickens westward over 400 km from <5 m near the forebulge to >150 m in the foredeep. Constituent allomembers are also wedge‐shaped but lack distinct clinothems, a rollover point or downlapping geometry. Ubiquitous wave ripples indicate that the sea floor lay above storm wave base. Deposition took place on an extremely low‐gradient ramp, where accommodation was limited by effective wave base. Lobate, river‐dominated deltas fringed the southern margin of the basin. The largest deltas are stacked in the same area, suggesting protracted stability of the feeder river. A buried palaeo‐valley on the underlying sub‐Cretaceous unconformity may have influenced compaction and controlled river location for ca 3 Myr. Adjacent to the western Cordillera, a predominantly mudstone succession is interbedded with abundant storm beds of very fine‐grained sandstone and siltstone that reflect supply from the adjacent orogen. Bioturbation indices in the Harmon alloformation range from zero to six which reflects the influence of stressors related to river‐mouth proximity. Harmon alloformation mudstone grades abruptly upward into marine sandstone and conglomerate of the overlying Cadotte alloformation. The Cadotte is composed of three allomembers ‘CA’ to ‘CC’, that represent the deposits of prograding strandplains 200 × 300 km in extent. Allomembers ‘CA’ and ‘CB’ are strongly sandstone‐dominated, whereas allomember ‘CC’ contains abundant conglomerate in the west. The dominantly aggradational wedge of Harmon alloformation mudstone records flexural subsidence driven by active thickening in the adjacent orogen: the high accommodation rate trapped coarser clastic detritus close to the basin margin. In contrast, the tabular, highly progradational sandstone and conglomerate bodies of the Cadotte alloformation record a low subsidence rate, implying tectonic quiescence in the adjacent orogen. Erosional unloading of the orogen through Cadotte time steepened rivers to the extent that they delivered gravel to the shore. These observations support an ‘anti‐tectonic’ model of gravel supply proposed previously for the United States portion of the Cretaceous foreland basin. Because Cadotte allomembers do not thicken appreciably into the foredeep, accommodation changes that controlled these transgressive–regressive successions were probably of eustatic origin.

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    Sedimentology
    Article . 2016
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    Authors: D. D. Maharaj; Gabriele Sala; Casey Marjerrison; Matthew B. Stone; +2 Authors

    Time-of-flight inelastic neutron scattering measurements have been carried out on polycrystalline samples of the $4{d}^{3}$ and $5{d}^{3}$ double pervoskite antiferromagnets ${\mathrm{La}}_{2}{\mathrm{LiRuO}}_{6}$ and ${\mathrm{La}}_{2}{\mathrm{LiOsO}}_{6}$. These reveal the development of an inelastic spin gap in ${\mathrm{La}}_{2}{\mathrm{LiRuO}}_{6}$ and ${\mathrm{La}}_{2}{\mathrm{LiOsO}}_{6}$ of $\ensuremath{\sim}1.8(8)$ and 6(1) meV, below their respective ordering temperatures ${T}_{N},\phantom{\rule{0.28em}{0ex}}\ensuremath{\sim}23.8$ and 30 K. The bandwidths of the spin excitations are shown to be $\ensuremath{\sim}5.7(9)\phantom{\rule{0.28em}{0ex}}\text{and}\phantom{\rule{0.28em}{0ex}}12(1)\phantom{\rule{0.28em}{0ex}}\mathrm{meV}$, respectively, at low temperatures. Spin gaps are surprising in such magnets as the ${t}_{2g}$ levels of ${\mathrm{Ru}}^{5+}$ or ${\mathrm{Os}}^{5+}$ are expected to be half-filled, resulting in an anticipated orbital singlet for both materials. We compare these results in monoclinic double perovskites ${\mathrm{La}}_{2}{\mathrm{LiRuO}}_{6}$ and ${\mathrm{La}}_{2}{\mathrm{LiOsO}}_{6}$ with those in cubic ${\mathrm{Ba}}_{2}{\mathrm{YRuO}}_{6}$ and ${\mathrm{Ba}}_{2}{\mathrm{YOsO}}_{6}$ as well as with those in other monoclinic ${\mathrm{La}}_{2}{\mathrm{NaRuO}}_{6},\phantom{\rule{0.28em}{0ex}}{\mathrm{La}}_{2}{\mathrm{NaOsO}}_{6}$, and ${\mathrm{Sr}}_{2}{\mathrm{ScOsO}}_{6}$ and model the inelastic magnetic scattering with linear spin-wave theory using minimal anisotropic exchange interactions. We discuss the possible role of the distortion of the face-centered-cubic double perovskite structure on the spin gap formation and geometric frustration in these materials and show that ${T}_{N}$ scales with the top of the spin-wave band in all members of these families that display long-range order.

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    https://doi.org/10.1103/physre...
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      https://doi.org/10.1103/physre...
      Article . 2018
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    Authors: Banyar Aung; Margaret Y. Gruber; Lisa Amyot; Khaled W. Omari; +2 Authors

    MicroRNA156 (miR156) is a regulator of flowering time and biomass production through regulation of members of SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) gene family. To expand our investigations on the utility of miR156 in alfalfa, we generated transgenic alfalfa expressing a heterologous miR156 from Lotus japonicus (LjmiR156a). 5′ RACE and qRT-PCR analysis confirmed that the same three SPL genes (MsSPL6, MsSPL12, and MsSPL13) targeted by MsmiR156d are also targets of LjmiR156a in alfalfa. Ectopic expression of LjmiR156a down-regulated these SPL genes in transgenic alfalfa, coupled with reduced internode length, a more extreme delay in flowering time than occurred with MsmiR156d, enhanced shoot branching, and elevated biomass production. While root length was maintained, nodulation was reduced in some transgenic genotypes. Furthermore, heterologous expression of LjmiR156a enhanced the contents of starch, soluble sugars, and phenolics in all transgenic genotypes in contrast to the impact from MsmiR156d enhancement, even though the effects on lignin, cellulose, pectin, structural sugars, flavonoids, and carotenoids were variable among the new alfalfa genotypes. The variations among the traits/genotypes reflect the change in expression of alfalfa SPL genes targeted by LjmiR156a and show that LjmiR156a could be employed as a tool to improve quality and yield of alfalfa biomass.

    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Plant Biotechnology ...arrow_drop_down
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    Plant Biotechnology Reports
    Article . 2015
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      image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
      Plant Biotechnology Reports
      Article . 2015
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    Authors: Diganta Sarkar; Riley Hooper; Abhoy Karmakar; Victor Terskikh; +1 Authors

    We report a rapid solid−state 35/37Cl NMR strategy for 3D organic−inorganic hybrid and low−dimensional (2D and 0D) all−inorganic lead−based perovskites embracing ultra-wideline acquisition approaches and moderate to ultrahigh magnetic fields. The observed quadrupolar NMR parameters (CQ and η), supported by GIPAW−DFT computations, revealed distinct features for unique local Cl environments with the variation of the A−site and dimensionality. 35Cl CQ values display the potential for becoming an informative probe of distinct Cl chemical environments.

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    https://doi.org/10.26434/chemr...
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      https://doi.org/10.26434/chemr...
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    Authors: G A, Wood; D S, Sarma; M C, Archer;

    Previously, we have shown that Copenhagen (Cop) rats are highly resistant to the induction of putative preneoplastic, glutathione S-transferase 7-7 (GST 7-7)-positive liver lesions following treatment with a modified resistant hepatocyte protocol. The objective of the current study was to establish the time course for the development of resistance and examine potential resistance mechanisms in Cop rats using F344 rats as susceptible controls. Male Cop and F344 rats (n = 25), 7-8 weeks of age, were initiated with diethylnitrosamine (200 mg/kg) and promoted 3 weeks later with four doses of 2-acetylaminofluorene (20 mg/kg) and a 2/3 partial hepatectomy (PH). Groups of rats from each strain were killed on days 2, 4, 7, 14 and 21 post-PH, 2 h after receiving bromodeoxyuridine. Cop livers contained similar numbers of GST 7-7-positive lesions to F344 livers on days 2 and 4 post-PH. The percent volume of liver occupied by these lesions did not differ between the strains on days 2, 4 and 7 post-PH. On day 14, however, approximately 29% of the liver volume in F344 rats was occupied by lesions, whereas in Cop rats this was significantly less (approximately 9%, P0.001). On day 21, lesions occupied approximately 58% of F344 rat livers and only approximately 6% of Cop livers. Despite these differences, the labeling index of hepatocytes was not significantly different between the strains at any time point, either within lesions or within surrounding normal liver. Furthermore, the apoptotic indices were not different between the strains at any time. However, differences were found in the extent of lesion remodeling (redifferentiation) and in the pattern of oval cell response following PH in Cop livers. By day 14 post-PH, approximately 76% of Cop liver lesions showed evidence of remodeling, compared with only approximately 14% of F344 lesions. The oval cell response to PH was equivalent in the two strains up to day 4 post-PH but by day 7, in F344 livers there was extensive migration of these cells into the liver parenchyma, whereas in Cop livers, the response remained localized to the portal regions. These results suggest that Cop resistance occurs at the promotion stage and not the initiation stage of carcinogenesis. Resistance appears not to be due to a lower proliferation rate nor to a higher apoptotic rate within Cop lesions. Precocious remodeling and/or a diminished oval cell response, however, may contribute to the resistance of Cop rats to the growth of GST 7-7-positive hepatic lesions.

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    Carcinogenesis
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    Carcinogenesis
    Article . 1999