Clathrate hydrates are specific cage-like structures formed by water molecules around a guest molecule. Despite the many studies that have been performed on clathrate hydrates, the actual molecular mechanism of both their homogeneous and heterogeneous nucleation has yet...

Prefluorescent radical probes, in which fluorescence is activated by radical trapping, and photoinitiators were used to detect radical generation in polymer films using fluorescence spectroscopy and microscopy. Prefluorescent radical probes are the foundation of a fluor...

High-valent multimetallic-oxo/oxyl species have been implicated as intermediates in oxidative catalysis involving proton-coupled electron transfer (PCET) reactions, but the reactive nature of these oxo species has hindered the development of an in-depth understanding of...

The 20S proteasome core particle is a molecular machine that plays a central role in the regulation of cellular function through proteolysis, and it has emerged as a valuable drug target for certain classes of cancers. Central to the development of new and potent pharma...

A new technique for preparing metal cluster complexes of a desired nuclearity by co-depositing ligand with metal clusters mass-selected from a cluster beam is illustrated by the deposition of Fe, Fe2, and Fe3 with excess CO. The matrices formed were studied by Fourier t...

In the past three years, machine learning (ML) in combination with density functional theory (DFT) has enabled computational screening of compounds with the goal of accelerated materials discovery....

An in-hole nanohole surface plasmon resonance sensing scheme is demonstrated. Arrays of periodic nanoholes milled through thin layers of SiO(x) and gold were used to detect the binding of organic and biological molecules inside the nanoholes, while blocking the gold sur...

Proton NMR imaging was used to investigate in situ the distribution of water in a polymer electrolyte membrane fuel cell operating on H2 and O2. In a single experiment, water was monitored in the gas flow channels, the membrane electrode assembly, and in the membrane su...

Herein we describe a catalytic tethering strategy in which simple aldehyde precatalysts enable, through temporary intramolecularity, room-temperature intermolecular hydroamination reactivity and the synthesis of vicinal diamines. The catalyst allows the formation of a m...