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Notaris saat ini diperbolehkan melakukan sertifikasi dokumen elektronik. Kewenangan ini termaktub dalam Pasal 15 ayat (3) Undang-Undang Nomor 2 Tahun 2014 Tentang Jabatan Notaris. Selain mengesahkan akta, notaris juga dapat menyimpan berkas dalam bentuk file. Namun, tidak sedikit notaris yang masih enggan menggunakan teknologi untuk membuat dan mengesahkan sebuah akta dikarenakan adanya pertentangan antar pasal baik dalam Undang-Undang Jabatan Notaris sendiri maupun dengan pasal dalam Undang-Undang lainnya. Penelitian ini bertujuan untuk mengetahui apakah akta yang menggunakan teknologi informatika memiliki kekuatan pembuktian layaknya akta autentik dan apakah sertifikasi elektronik yang dilakukan oleh notaris sejalan dengan tugas dan jabatan notaris. Metode penelitian yang digunakan yaitu jenis penelitian hukum normatif yang dilakukan dengan cara penelaahan bahan pustaka atau data sekunder dengan menggunakan pendekatan undang-undang dan pendekatan konseptual. Penelitian ini berfokus pada akta hasil Rapat Umum Pemegang Saham Luar Biasa PT. Lippo Karawaci. Tbk yang dilakukan melalui video konferensi pada tanggal 13 Oktober 2021. Adanya ketidaksepakatan dari beberapa pemegang saham atas sertifikasi yang dilakukan secara elektronik karena dinilai dapat membuat akta tersebut menjadi akta di bawah tangan. Selain adanya pertentangan antara pasal, hal ini juga disebabkan tidak adanya peraturan pelaksana terkait pembuatan akta melalui teknologi informasi (Cyber Notary) oleh notaris sehingga perlunya pengkajian ulang terhadap Undang-Undang terkait dan pembuatan peraturan pelaksana khusus cyber notary.

Supplementary data for: [https://doi.org/10.1016/j.lwt.2017.08.060] Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/2552] Related to accepted version: [http://cherry.chem.bg.ac.rs/handle/123456789/2989]

Salmonella Typhimurium ST313 causes invasive nontyphoidal Salmonella (iNTS) disease in sub-Saharan Africa, targeting susceptible HIV + , malarial or malnourished individuals. An in-depth genomic comparison between the ST313 isolate D23580, and the well-characterized ST19 isolate 4/74 that causes gastroenteritis across the globe, revealed extensive synteny. To understand how the 856 nucleotide variations generated phenotypic differences, we devised a large-scale experimental approach that involved the global gene expression analysis of strains D23580 and 4/74 grown in sixteen infection-relevant growth conditions. Comparison of transcriptional patterns identified virulence and metabolic genes that were differentially expressed between D23580 versus 4/74, many of which were validated by proteomics. We also uncovered the S. Typhimurium D23580 and 4/74 genes that showed expression differences during infection of murine macrophages. Our comparative transcriptomic data are presented in a new enhanced version of the Salmonella expression compendium SalComD23580: bioinf.gen.tcd.ie/cgi-bin/salcom_v2.pl . We discovered that the ablation of melibiose utilization was caused by 3 independent SNP mutations in D23580 that are shared across ST313 lineage 2, suggesting that the ability to catabolise this carbon source has been negatively selected during ST313 evolution. The data revealed a novel plasmid maintenance system involving a plasmid-encoded CysS cysteinyl-tRNA synthetase, highlighting the power of large-scale comparative multi-condition analyses to pinpoint key phenotypic differences between bacterial pathovariants.

Streamflow in south-central Chile (SCC, ∼ 37–42∘ S) is vital for agriculture, forestry production, hydroelectricity, and human consumption. Recent drought episodes have generated hydrological deficits with damaging effects on these activities. This region is projected to undergo major reductions in water availability, concomitant with projected increases in water demand. However, the lack of long-term records hampers the development of accurate estimations of natural variability and trends. In order to provide more information on long-term streamflow variability and trends in SCC, here we report findings of an analysis of instrumental records and a tree-ring reconstruction of the summer streamflow of the Río Imperial (∼ 37∘ 40′ S–38∘ 50′ S). This is the first reconstruction in Chile targeted at this season. Results from the instrumental streamflow record (∼ 1940 onwards) indicated that the hydrological regime is fundamentally pluvial with a small snowmelt contribution during spring, and evidenced a decreasing trend, both for the summer and the full annual record. The reconstruction showed that streamflow below the average characterized the post-1980 period, with more frequent, but not more intense, drought episodes. We additionally found that the recent positive phase of the Southern Annular Mode has significantly influenced streamflow. These findings agree with previous studies, suggesting a robust regional signal and a shift to a new hydrological scenario. In this paper, we also discuss implications of these results for water managers and stakeholders; we provide rationale and examples that support the need for the incorporation of tree-ring reconstructions into water resources management.

Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) offers micron-resolution 2D chemical imaging, which has been adapted recently to ice core analysis. Measurements were performed in 2020 at the Ca’Foscari University of Venice, in order to investigate the localization of impurities in the ice samples. Here an image is presented from applying LA-ICP-MS elemental imaging to a glacial (MIS2, bag 1065) samples of the EPICA Dome C ice core from central Antarctica. Lateral resolution is 35 microns both along and perpendicular to the scan direction. Considered as analytes are 23Na, 25Mg and 88Sr. Background and drift correction as well as image construction were performed using the software HDIP (Teledyne Photon Machines, Bozeman, MT, USA). Impurity images are acquired as a pattern of lines, without overlap in the direction perpendicular to that of the scan, and without any further spatial interpolation. Each pixel in an ice core chemical image has a size of 35 μm x 35 μm. For each chemical element the datasets comprise a numerical matrix which contains rows and columns according to the physical size of the image: an image of 7 mm x 35 mm in size has 200 rows and 1000 columns. The numerical entries in this matrix refer to the recorded intensity (e.g. in counts). Values lower than the detection limit are set to zero. Due to the careful synchronization, the individual pixels of the different chemical channels can be considered to be almost perfectly spatially aligned. In contrast, the mosaic of visual images obtained from the laser camera is not a-priori aligned with the chemical images. The visual images are generally characterized by air bubbles (dark blobs), grain boundaries (dark lines) and occasional sub-grain boundaries (thin dark lines).

The Stratosphere–troposphere Processes And their Role in Climate (SPARC) Quasi-Biennial Oscillation initiative (QBOi) aims to improve the fidelity of tropical stratospheric variability in general circulation and Earth system models by conducting coordinated numerical experiments and analysis. In the equatorial stratosphere, the QBO is the most conspicuous mode of variability. Five coordinated experiments have therefore been designed to (i) evaluate and compare the verisimilitude of modelled QBOs under present-day conditions, (ii) identify robustness (or alternatively the spread and uncertainty) in the simulated QBO response to commonly imposed changes in model climate forcings (e.g. a doubling of CO2 amounts), and (iii) examine model dependence of QBO predictability. This paper documents these experiments and the recommended output diagnostics. The rationale behind the experimental design and choice of diagnostics is presented. To facilitate scientific interpretation of the results in other planned QBOi studies, consistent descriptions of the models performing each experiment set are given, with those aspects particularly relevant for simulating the QBO tabulated for easy comparison.