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5,400 research outcomes, page 1 of 540
  • publication . Article . 2019
    Open Access English
    Authors:
    Rachel Lane; Ladislav Tomasek; Lydia B. Zablotska; Estelle Rage; Franco Momoli; Julian Little;
    Persistent Identifiers
    Publisher: HAL CCSD

    It is well established that high radon exposures increase the risk of lung cancer mortality. The effects of low occupational exposures and the factors that confound and modify this risk are not clear and are needed to inform current radiation protection of miners. The r...

  • publication . Article . 2021
    Open Access
    Authors:
    Lauren G. Friedman; Nicholas McKeehan; Yuko Hara; Jeffrey L. Cummings; Dawn C. Matthews; Jian Zhu; Richard C. Mohs; Deli Wang; Suzanne Hendrix; Melanie Quintana; ...
    Persistent Identifiers
    Publisher: eScholarship, University of California

    Drug development for Alzheimer disease and other neurodegenerative dementias, including frontotemporal dementia, has experienced a long history of phase 2 and phase 3 clinical trials that failed to show efficacy of investigational drugs. Despite differences in clinical ...

  • publication . Article . 2019
    Open Access English
    Authors:
    Ghita, Mihaela; Brown, Kathryn H.; Kelada, Olivia J.; Graves, Edward E.; Butterworth, Karl T.;
    Persistent Identifiers
    Publisher: MDPI AG
    Project: UKRI | Refinement of soft tissue... (NC/R001553/1)

    Translational research aims to provide direct support for advancing novel treatment approaches in oncology towards improving patient outcomes. Preclinical studies have a central role in this process and the ability to accurately model biological and physical aspects of ...

  • publication . Article . 2017
    Open Access English
    Authors:
    Ali Tamayol; Alireza Hassani Najafabadi; Pooria Mostafalu; Ali K. Yetisen; Mattia Commotto; Musab Aldhahri; Mohamed Shaaban Abdel-wahab; Zeynab Izadi Najafabadi; Shahrzad Latifi; Mohsen Akbari; ...
    Persistent Identifiers
    Publisher: Nature Publishing Group UK
    Project: NSF | EFRI-BioFLEX: Tissue Engi... (1240443), NIH | A Microfabrication Platfo... (1R01EB012597-01), NIH | Microengineered Osteons f... (5R01AR057837-04), NIH | 3D combinatorial microenv... (5R01HL099073-02), NIH | Engineering Vascularized ... (7R01DE021468-02), NIH | Microfabricated Vasculari... (5R01HL092836-02), NIH | ENDOTHELIUM-DERIVED RELAX... (5F32HL008392-02), NIH | Microengineered environme... (5RL1DE019024-03)

    The optical phase conjugation (OPC) through photonic nanostructures in coherent optics involves the utilization of a nonlinear optical mechanism through real-time processing of electromagnetic fields. Their applications include spectroscopy, optical tomography, wavefron...

  • publication . Article . 2019
    Open Access English
    Authors:
    Medeiros, Cynthia B.; Moxon‐Emre, Iska; Scantlebury, Nadia; Malkin, David; Ramaswamy, Vijay; Decker, Alexandra; Law, Nicole; Kumabe, Toshihiro; Leonard, Jeffrey; Rubin, Josh; ...
    Persistent Identifiers
    Publisher: Wiley

    Despite the significant advances in our knowledge of medulloblastoma and the resulting advantages of improved therapy, health related quality of life (HRQL) requires further attention globally. Assessing HRQL in an international sample, we found that the majority of pat...

  • publication . Article . Other literature type . 2014
    Open Access
    Authors:
    Chandra L. Ford; Sung-Jae Lee; Steven P. Wallace; Terry T. Nakazono; Peter A. Newman; William E. Cunningham;
    Persistent Identifiers
    Publisher: eScholarship, University of California

    © 2014 Taylor Francis. The Centers for Disease Control and Prevention recommends routine human immunodeficiency virus (HIV) testing of every client presenting for services in venues where HIV prevalence is high. Because older adults (aged ≥50 years) have particularly po...

  • publication . Article . 2019
    Open Access
    Authors:
    Konstantinos Arfanakis; John Morris; Julia Neitzel; Anton Porsteinsson; John Hsiao; Bruce Miller; Laura Ponto; Ging-Yuek Hsiung; Peter Snyder; Howard Feldman; ...
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Project: EC | VASCAMY (334259), NIH | Alzheimers Disease Neuroi... (1U01AG024904-01), CIHR

    The single nucleotide polymorphism (SNP) rs744373 in the bridging integrator-1 gene (BIN1) is a risk factor for Alzheimer’s disease (AD). In the brain, BIN1 is involved in endocytosis and sustaining cytoskeleton integrity. Post-mortem and in vitro studies suggest that B...

  • publication . Article . 2018
    Open Access
    Authors:
    Luke W. Bonham; Luke W. Bonham; Ethan G. Geier; Natasha Z. R. Steele; Dominic Holland; Bruce L. Miller; Anders M. Dale; Anders M. Dale; Anders M. Dale; Rahul S. Desikan; ...
    Persistent Identifiers
    Publisher: Frontiers Media SA
    Project: NIH | RNA signatures of frontot... (5K01AG049152-03), NIH | Alzheimers Disease Neuroi... (1U01AG024904-01), NIH | DATA MANAGEMENT AND BIOST... (5P50AG023501-03), CIHR

    There is increasing evidence that metabolic dysfunction plays an important role in Alzheimer’s disease (AD). Brain insulin resistance and subsequent impairment of insulin and insulin-like growth factor (IGF) signaling are associated with the neurodegenerative and clinic...

  • publication . Article . Preprint . 2022
    Open Access English
    Authors:
    Philipp G. Sämann; Juan Eugenio Iglesias; Boris A. Gutman; Dominik Grotegerd; Ramona Leenings; Claas Flint; Udo Dannlowski; Emily K. Clarke-Rubright; Rajendra A. Morey; Theo G.M. van Erp; ...
    Project: EC | BUNGEE-TOOLS (677697)

    Hippocampal subfield analysis is increasingly performed with the availability of automated magnetic resonance imaging segmentation methods. We give a synopsis of the FreeSurfer hippocampal subfield segmentation algorithm, measurement reliability studies and application ...

  • publication . Article . Preprint . 2016
    Open Access English
    Authors:
    Chai Lor; Joseph Lopes; Michelle K. Mattson-Hoss; Jing Xu; Linda S. Hirst;
    Persistent Identifiers
    Project: NSF | CAREER: Self-Assembly of ... (0852791)

    The presence of membrane tubules in living cells is essential to many biological processes. In cells, one mechanism to form nano-sized lipid tubules is via molecular motor induced bilayer extraction. In this paper, we describe a simple experimental model to investigate ...

5,400 research outcomes, page 1 of 540