PreSens Precision Sensing (Germany)
PreSens Precision Sensing (Germany)
7 Projects, page 1 of 2
Open Access Mandate for Publications assignment_turned_in Project2013 - 2016 LUMC, PreSens Precision Sensing (Germany), ABER INSTRUMENTS LIMITED, XPAND BIOTECHNOLOGY BVLUMC,PreSens Precision Sensing (Germany),ABER INSTRUMENTS LIMITED,XPAND BIOTECHNOLOGY BVFunder: EC Project Code: 601869All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=corda_______::a9a892c85c2a575dc68d806ea460c6d3&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euvisibility 25visibility views 25 download downloads 28 Powered bymore_vert All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=corda_______::a9a892c85c2a575dc68d806ea460c6d3&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euOpen Access Mandate for Publications assignment_turned_in Project2013 - 2016 PreSens Precision Sensing (Germany), 3H Biomedical AB, TECL, KTH, STOBBE TECH ASPreSens Precision Sensing (Germany),3H Biomedical AB,TECL,KTH,STOBBE TECH ASFunder: EC Project Code: 601700All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=corda_______::f60c3469def130b085fb12d7ff76fc4b&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=corda_______::f60c3469def130b085fb12d7ff76fc4b&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euOpen Access Mandate for Publications and Research data assignment_turned_in Project2019 - 2024 CYPROTEX DISCOVERY LIMITED, UNIVERSITA DEGLI STUDI DI PARMA, Atturos, UM, ULB +4 partnersCYPROTEX DISCOVERY LIMITED,UNIVERSITA DEGLI STUDI DI PARMA,Atturos,UM,ULB,UCD,CNR,ARTTIC,PreSens Precision Sensing (Germany)Funder: EC Project Code: 825745Overall Budget: 5,655,090 EURFunder Contribution: 5,655,090 EURSCREENED will develop 3 different three-dimensional (3D) in vitro assays based on rodent and human thyroid cell constructs. At different level of anatomical complexity, these assays will increasingly mimic the structure and function of the native thyroid gland, ultimately achieving the replication of its vascular anatomy and morphogenetic characteristics: 1) a 3D organoid based on stem-cell derived thyroid cells, 2) a decellularized scaffold able to reproduce the biological composition of a native thyroid, repopulated by the 3D organoids, and 3) a bioprinted construct with the 3D organoids able to mimic the spatial and geometrical architecture of a native thyroid. These 3D assays will be hosted in a modular microbioreactor equipped with innovative sensing technology and enabling precise control of cell culture conditions. New superparamagnetic biocompatible and biomimetic particles will be used to produce “magnetic cells” to support precise spatiotemporal homing of the cells in the 3D decellularized and bioprinted constructs. The 3D assays will be used to screen the effect of endocrine disruptors (EDs) on the thyroid function in a unique biological sex-specific approach. Their performance will be assessed individually, in comparison with each other, and against in vivo studies. The 3D assays are expected to predict with more sensitivity and specificity the thyroid responses to different classes of EDs at low doses, compared to classical 2D in vitro assays or animal models. Supporting the “Adverse Outcome Pathway” concept, proteogenomics analysis and biological modelling of the underlying mode of action will be used to gain a mechanistic understanding of the chain of events from exposure to adverse effects on thyroid development and function. For future uptake, SCREENED will engage discussion with relevant stakeholder groups, including regulatory bodies and industry, to ensure that the assays are fit for purpose for ED safety assessment
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For further information contact us at helpdesk@openaire.euassignment_turned_in Project2009 - 2012 University of Freiburg, IBA, TEKNOLOGIAN TUTKIMUSKESKUS VTT OY, GALILAEUS OY, CNRS +4 partnersUniversity of Freiburg,IBA,TEKNOLOGIAN TUTKIMUSKESKUS VTT OY,GALILAEUS OY,CNRS,PreSens Precision Sensing (Germany),Microsaic Systems,DS,EPFLFunder: EC Project Code: 227243All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=corda_______::e1a8e15c99061dc0475b37ca8488ccc8&type=result"></script>'); --> </script>
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For further information contact us at helpdesk@openaire.euOpen Access Mandate for Publications assignment_turned_in Project2011 - 2015 University of Bristol, OCTANE, FINCERAMIC, IOR, UNIZG +4 partnersUniversity of Bristol,OCTANE,FINCERAMIC,IOR,UNIZG,HOLOSTEM,USB,PreSens Precision Sensing (Germany),CELLEC BIOTEK AGFunder: EC Project Code: 278807All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=corda_______::16988fd90e19fd0b2fb23251131a7b40&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euvisibility 39visibility views 39 download downloads 50 Powered bymore_vert All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=corda_______::16988fd90e19fd0b2fb23251131a7b40&type=result"></script>'); --> </script>
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