organization

iMM

INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES
53 projects, page 1 of 11
  • project . 2021 - 2023
    Funder: EC Project Code: 101003392
    Overall Budget: 159,815 EURFunder Contribution: 159,815 EUR
    Open Access mandate for Publications and Research Data
    Partners: iMM

    Immune cells constitute a major component of the tumor microenvironment (TME) that influence several aspects of cancer progression and outcome. The host laboratory has identified two distinct γδ T-cell subsets with opposing roles in tumor progression: whereas interferon...

  • project . 2017 - 2019
    Funder: EC Project Code: 743640
    Overall Budget: 160,636 EURFunder Contribution: 160,636 EUR
    Open Access mandate for Publications
    Partners: iMM

    Cancer remains a leading cause of death and morbidity worldwide. Prostate cancer (PC) is among the most frequently diagnosed non-skin cancers. Despite major advances in the understanding of cancer biology and development of candidate therapeutic agents, there is still a...

  • project . 2019 - 2022
    Funder: EC Project Code: 842498
    Overall Budget: 147,815 EURFunder Contribution: 147,815 EUR
    Open Access mandate for Publications
    Partners: iMM

    The formation of a functional patterned (adaptation) vascular network is essential for development, tissue growth, and organ physiology. Several human vascular disorders arise from the mis-patterning (maladaptation) of blood vessels, such as arteriovenous malformations,...

  • project . 2016 - 2018
    Funder: EC Project Code: 713612
    Overall Budget: 150,000 EURFunder Contribution: 150,000 EUR
    Open Access mandate for Publications
    Partners: iMM

    MUSCLEGUY represents a unique opportunity to commercialize a novel 3D in vitro system for screening and validation of drug candidates to treat muscle disorders. Although skeletal muscle disorders are relatively rare they pose a huge socioeconomic burden. Currently there...

  • project . 2020 - 2022
    Funder: EC Project Code: 842695
    Overall Budget: 147,815 EURFunder Contribution: 147,815 EUR
    Open Access mandate for Publications
    Partners: iMM

    The need to preserve correct splicing is a major source of constraint on sequence evolution. This includes selection on the splice sites as well as on regulatory elements in exons and introns. Are all exons and introns constrained similarly by splicing related pressures...

53 projects, page 1 of 11
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