SUNDHED.DK

Millions of Europeans undergo optical colonoscopy (OC) every year. OC may be associated with discomfort, complications and sick-days, which affect acceptability, and constitutes a heavy burden on European hospital capacities. Colon capsule endoscopy (CCE) is a new technology, which has the potential to replace 50 ? 65 % of all OCs. CCE is preferred by patients, has a lower complication rate and can be performed out of hospital. CCE holds great potential for both patients and hospitals. However, the diagnostic process of CCE includes a time-consuming manual reading done by trained personnel and is expensive and prone to human error. For CCE to be a viable alternative to OC these challenges need to be addressed. Thus, our goal is to create a complete and validated AI-assisted pathway that improves CCE diagnostics making the technology clinically viable for the good of patients, health care systems and society. We have already completed development of several AI algorithms (AIA) for CCE diagnostics, and more will be completed within 1 ?2 years. The AICE concept will focus on: 1) completing development of the remaining AIAs, 2) external validation the all AIAs, 3) creating a clinical support system for data handling, storage and transmission, 4) developing a diagnostic pathway that considers quality, efficiency, patient preferences, ethics and economy 5) promotes the integration of AICE solutions into clinical practice via guidelines and upscaling adjustments. To achieve these goals, AICE will use an unprecedented large and diverse collection of existing patient data from nation-wide clinical studies, and will include extensive initiatives in the fields of ethics, communication and patient engagement. To ensure the right competences are present, AICE brings together clinical researchers, epidemiologists, data scientists, digital health experts, health economists, ethics researchers, SMEs, communication experts and experts in regulatory affairs.

KONFIDO advances the state of the art of eHealth technology with respect to four key dimensions of digital security, namely: data preservation, data access and modification, data exchange, and interoperability and compliance. To address the challenges of secure storage and exchange of eHealth data, protection and control over personal data, and security of health related data gathered by mobile devices, KONFIDO takes a holistic approach – i.e. one targeting all the architectural layers of an IT infrastructure, and specifically: storage, dissemination, processing, and presentation. KONFIDO builds on and extends the results of a best of breed selection of successful projects, notably: epSOS, STORK, DECIPHER, EXPAND, and ANTILOPE. The approach will be implemented in a technological framework that relies on six technology pillars: 1) security extensions provided by main CPU vendors; 2) security solutions based on photonic technologies; 3) homomorphic encryption mechanisms; 4) customised STORK-compliant eID support; 5) customized extensions of selected SIEM solutions; and 6) disruptive logging and auditing mechanisms. The usability of the proposed solutions will be tested in a realistic setup, deployed on top of a federated cloud infrastructure, where data will be exchanged and services interoperate cross-border. Experimental evidence will be collected, proving that KONFIDO solutions provide effective protection even against attacks by privileged software (e.g. the Operating System or the Hypervisor) or privileged users (e.g. the System Administrator or the Cloud Provider). Since i) it builds on results that were already widely accepted, and ii) it relies on a handful of complementary technologies (some of which are already at a high level of maturity), KONFIDO has a dramatic potential in terms of innovation in the field of coordinated care towards improved quality of healthcare solutions.