organization

UKRI

UNITED KINGDOM RESEARCH AND INNOVATION
333 projects, page 1 of 67
  • project . 2019 - 2021
    Funder: EC Project Code: 839899
    Overall Budget: 224,934 EURFunder Contribution: 224,934 EUR
    Open Access mandate for Publications and Research Data
    Partners: UKRI

    Deciphering how nucleic acids replicated in the absence of genetically encoded enzymes is of critical importance to understanding the onset of Darwinian evolution. While much effort has been put into developing chemically-driven copying of RNA exploiting activated monom...

  • project . 2020 - 2022
    Funder: EC Project Code: 894039
    Overall Budget: 212,934 EURFunder Contribution: 212,934 EUR
    Open Access mandate for Publications and Research Data
    Partners: UKRI

    What defines the functional specialization of a cell is its unique proteome. Proteins need to be translated and properly folded to ensure their biological function. Several protein quality control pathways have arisen during evolution, some of them specialized in monito...

  • project . 2020 - 2022
    Funder: EC Project Code: 896454
    Overall Budget: 224,934 EURFunder Contribution: 224,934 EUR
    Open Access mandate for Publications
    Partners: UKRI

    The immune system is indispensable for our defense against infections, and plays an essential role in homeostasis, where compartmentalization and specialization are key aspects of every immune cell. Microenvironmental cues (e.g. stromal cell-derived signals) are integra...

  • project . 2020 - 2022
    Funder: EC Project Code: 895412
    Overall Budget: 224,934 EURFunder Contribution: 224,934 EUR
    Open Access mandate for Publications and Research Data
    Partners: UKRI

    Electron cryo-microscopy (cryo-EM) is the fastest growing technique to explore the structure of biological macromolecules. To limit radiation damage, images are recorded under low-dose conditions, which leads to high levels of experimental noise. To reduce the noise, on...

  • project . 2019 - 2021
    Funder: EC Project Code: 832620
    Overall Budget: 212,934 EURFunder Contribution: 212,934 EUR
    Open Access mandate for Publications and Research Data
    Partners: UKRI

    G protein coupled receptors (GPCRs) are key regulators of cell homeostasis. Given their importance in cell physiology, they have been extensively exploited as drug targets. Despite this, many discordant observations on receptor signalling and on GPCR drug response remai...

333 projects, page 1 of 67
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