research product . 2018

Evolutionary GEM: The Evolution of Methicillin-resistant Staphylococcus aureus

Tu, Jaiden; Gray, Patricia M.;
Open Access
  • Published: 20 Mar 2018
  • Publisher: Scholarship@Western
  • Country: Canada
Abstract
Since 1961, methicillin-resistant Staphylococcus aureus (MRSA) has evolved through both single locus gene variation and horizontal gene transfer. By the late 1970s, the emergence of new SCCmec allotypes marked the beginning of a worldwide MRSA pandemic. The continuous and rapid evolution of MRSA, in response to new antibiotics, remains a major public health issue worldwide.
Subjects
Medical Subject Headings: bacterial infections and mycosesbiochemical phenomena, metabolism, and nutrition
free text keywords: Methicillin-resistant Staphylococcus aureus, Evolution, Horizontal Gene Transfer, MRSA, HGT, Superbug, SCCmec, Biology
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