project . 2017 - 2023 . On going

IB4SD-TRISTAN

Imaging Biomarkers (IBs) for Safer Drugs: Validation of Translational Imaging Methods in Drug Safety Assessment - Sofia ref.: 116106
Open Access mandate for Publications European Commission
  • Funder: European CommissionProject code: 116106 Call for proposal: H2020-JTI-IMI2-2015-07-two-stage
  • Funded under: H2020 | IMI2-RIA Overall Budget: 22,724,600 EURFunder Contribution: 12,000,000 EUR
  • Status: On going
  • Start Date
    01 Jan 2017
    End Date
    30 Jun 2023
  • Detailed project information (CORDIS)
  • Open Access mandate
    Research Data: No
Description
1.Our consortium has broad, deep experience of drug development and imaging biomarker (IB) validation. We are internationally recognized experts in transporter biology, animal models of lung injury, toxicology, DCEMRI, compartmental modeling, 1H&129Xe lung MR, and labeling of biologicals with PET and fluorescence tags, together with physicians who care for relevant patients. We have an outstanding record of translating IBs: (a) into animals, (b) into man, (c) into tools which drug developers use with confidence in clinical trials of investigational agents, (d) into regulatory drug development and healthcare. We will develop and validate the required IBs and make...
Description
1.Our consortium has broad, deep experience of drug development and imaging biomarker (IB) validation. We are internationally recognized experts in transporter biology, animal models of lung injury, toxicology, DCEMRI, compartmental modeling, 1H&129Xe lung MR, and labeling of biologicals with PET and fluorescence tags, together with physicians who care for relevant patients. We have an outstanding record of translating IBs: (a) into animals, (b) into man, (c) into tools which drug developers use with confidence in clinical trials of investigational agents, (d) into regulatory drug development and healthcare. We will develop and validate the required IBs and make...
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