project . 2021 - 2027 . On going

SALAMANDRA

Decoding the organization and regeneration of locomotor neuronal networks in tetrapods by integrating genomics, systems neuroscience, numerical modeling, and biorobotics
Open Access mandate for Publications and Research DataOpen Access mandate for ... European Commission
  • Funder: European CommissionProject code: 951477 Call for proposal: ERC-2020-SyG
  • Funded under: H2020 | ERC | ERC-SyG Overall Budget: 9,559,650 EURFunder Contribution: 9,559,650 EUR
  • Status: On going
  • Start Date
    01 Sep 2021
    End Date
    31 Aug 2027
  • Detailed project information (CORDIS)
Description
The goals of this project are to decipher how the interplay between central and peripheral mechanisms controls locomotion in four legged animals (tetrapods) and to the delineate the reorganization of motor circuits linked to functional regeneration after spinal cord lesion. We will take advantage of the evolutionarily conserved traits of neural structures in vertebrates to address these two fundamental questions by using salamanders as model organisms. Salamanders are best suited to these aims for two main reasons: First, because they have an anatomically simplified nervous system, which yet possesses the main features of all tetrapods; second, because they have...
Description
The goals of this project are to decipher how the interplay between central and peripheral mechanisms controls locomotion in four legged animals (tetrapods) and to the delineate the reorganization of motor circuits linked to functional regeneration after spinal cord lesion. We will take advantage of the evolutionarily conserved traits of neural structures in vertebrates to address these two fundamental questions by using salamanders as model organisms. Salamanders are best suited to these aims for two main reasons: First, because they have an anatomically simplified nervous system, which yet possesses the main features of all tetrapods; second, because they have...
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