project . 2021 - 2021 . Closed

Understanding membrane curvature-induced lipid sorting through molecular simulation

UK Research and Innovation
  • Funder: UK Research and InnovationProject code: NE/V010026/1
  • Funded under: NERC Funder Contribution: 10,270 GBP
  • Status: Closed
  • Start Date
    01 Jan 2021
    End Date
    31 Dec 2021
Description
EPSRC : Paul Smith : EP/N509498/1 Lipids are biological molecules that have hydrophobic tails and hydrophilic headgroups. Along with proteins, lipids constitute the complex fluid mixture of biological cell membranes. There are hundreds of types of lipids in cell membranes, each with a different combination of tail and headgroup, and many serving important biological functions. The lateral organization of lipids - the way in which different lipid types mix with one another - also serves important but poorly understood biological roles, including providing platforms for transmitting signals across the membrane. Physics-based computer simulations offer a unique opp...
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Description
EPSRC : Paul Smith : EP/N509498/1 Lipids are biological molecules that have hydrophobic tails and hydrophilic headgroups. Along with proteins, lipids constitute the complex fluid mixture of biological cell membranes. There are hundreds of types of lipids in cell membranes, each with a different combination of tail and headgroup, and many serving important biological functions. The lateral organization of lipids - the way in which different lipid types mix with one another - also serves important but poorly understood biological roles, including providing platforms for transmitting signals across the membrane. Physics-based computer simulations offer a unique opp...
Partners
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